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High-efficiency quick-acting long-acting hangover-alleviating agent

A technology of anti-alcoholic and liver-protecting, hydrolyzed solution, applied in the field of anti-alcoholic agents, can solve problems such as excessive secretion of hydrochloric acid by gastric parietal cells, insufficiency of gastric mucosal defense, Helicobacter pylori infection, etc., achieve high pharmacological activity, reduce serum transaminase levels, The effect of short manufacturing process cycle

Inactive Publication Date: 2020-06-02
南京顶顶生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the pathological mechanism of peptic ulcer is not yet fully understood, the following three main pathogenic factors have been recognized: (1) excessive secretion of hydrochloric acid by gastric parietal cells; (2) insufficiency or damage of gastric mucosal defenses and (3) Helicobacter pylori infection

Method used

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  • High-efficiency quick-acting long-acting hangover-alleviating agent
  • High-efficiency quick-acting long-acting hangover-alleviating agent
  • High-efficiency quick-acting long-acting hangover-alleviating agent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0147] Example 1 Take 100 grams of fish skin, add 250 mL of deionized water, heat and extract at 100°C for 8 hours, homogenize, and after the homogenate is filtered, the filtrate is vacuum concentrated to 150mL. Spray drying under the condition of ℃ to obtain light yellow collagen dry powder.

[0148] An appropriate amount of the dry collagen powder was hydrolyzed with 6N hydrochloric acid at 110° C. for 24 hours, and the content of hydroxyproline was measured according to the Kivirikko method and the collagen content was converted. The result showed that the collagen content of the dry powder was 92%.

Embodiment 2

[0149] Example 2 Take 100 grams of swim bladder, add 1000 mL of deionized water, heat and extract at 110° C. under 2 atmospheric pressure for 30 minutes, homogenize, filter, concentrate the filtrate in vacuum to 350 mL, and spray dry to obtain light yellow collagen dry powder.

Embodiment 3

[0150] Example 3 Take 100 grams of fish skin, add 500 mL of deionized water, heat and extract at 100 ° C for 2 hours, filter, and set aside the filtrate, add 250 mL of water to the filter residue and extract the same, repeat the extraction for a total of 3 times, and finally use the filtrate to homogenize the residue , After the homogenate was filtered, it was concentrated in vacuum to ~200mL, and spray-dried to obtain light yellow collagen dry powder.

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Abstract

The invention discloses a composition with a hangover alleviating effect. The composition comprises collagen and a partial hydrolysate thereof, wherein the collagen comprises denatured collagen. According to the invention, fish, cattle and pigs are used as raw materials, and collagen or denatured collagen thereof, a mixture of the collagen and the denatured collagen thereof and the partial hydrolysate of the collagen are prepared through extraction, concentration and partial hydrolysis; and experiments prove that the collagen or the denatured collagen thereof and the partial hydrolysate of thecollagen have an excellent hangover alleviating effect and can be used for preparing hangover alleviating agents.

Description

technical field [0001] The invention belongs to the technical field of health food, and in particular relates to a hangover hangover agent with collagen and / or denatured collagen and partial hydrolyzate thereof as main active ingredients. Background technique [0002] More than 90% of ethanol that enters the body is metabolized in the liver. Under physiological conditions, alcohol is metabolized into acetaldehyde by liver alcohol dehydrogenase (ADH), and then converted into acetic acid by the action of acetaldehyde dehydrogenase (ALDH). Acetic acid is non-toxic And can be quickly metabolized into carbon dioxide and water. If the human body is fully equipped with these two alcohol metabolizing enzymes, it can decompose ethanol quickly. Alcohol dehydrogenase exists in the human body, and the quantity and activity are basically equal, but there are more people who lack acetaldehyde dehydrogenase. When acetaldehyde dehydrogenase is lacking or insufficient, acetaldehyde cannot ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/39A61P1/16A61P39/02A23L33/17A23L33/105A61K38/01A61K36/72
CPCA23V2002/00A61K36/232A61K36/48A61K36/72A61K38/011A61K38/39A23L33/105A23L33/17A61P1/16A61P39/02A61K2300/00A23V2200/334A23V2200/32A23V2250/5422
Inventor 汪海
Owner 南京顶顶生物科技有限公司
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