Composition with effects of exciting skin cell energy and repairing skin barrier as well as preparation method and application of composition

A technology for repairing skin and skin cells, applied in the field of skin care and beauty, can solve problems such as insignificant clinical effects, and achieve the effects of improving bioavailability and efficacy, controllable quality, and increasing skin elasticity

Active Publication Date: 2020-06-05
北京皓尔生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Some skin care products currently on the market often only target a certain manifestation, or several mechanisms of a certain manifestation, so the clinical effect is not obvious

Method used

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  • Composition with effects of exciting skin cell energy and repairing skin barrier as well as preparation method and application of composition
  • Composition with effects of exciting skin cell energy and repairing skin barrier as well as preparation method and application of composition
  • Composition with effects of exciting skin cell energy and repairing skin barrier as well as preparation method and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Formula: 1 part of ribose (natural source of extraction), 0.5 parts of kelp extract, 0.5 part of wakame extract, 0.5 part of fucus extract, 2 parts of glycerin, 5.5 parts of deionized water, 0.15 parts of antibacterial peptide

[0032] Preparation Process:

[0033] (1) Select fucus, kelp and wakame, then select and clean each raw material, remove thick stems and silt, filter the water, and pulverize each raw material with a pulverizer.

[0034] (2) Preparation of strain fermentation broth

[0035] Inoculate the Aspergillus niger strain in common mold soup medium, culture it on a shaker at 30°C and 200rpm for 6 days, when the mold content reaches 10 9 Above cfu / ml, stop fermentation and reserve;

[0036] (3) fermentation

[0037] Add pulverized Fucus or Kelpia Kelp or Undaria pinnatifida into the fermenter, add 10 times of water, then add (NH 4 ) 2 SO 4 0.2%, MgSO 4 0.15%, KH 2 PO 4 1%, peptone 1%, after stirring evenly, adjust the pH between 5.5 and 5.6, after ...

Embodiment 2

[0043] Formula: 1.6 parts of ribose (fermentation source), 0.6 parts of kelp extract, 0.8 parts of wakame extract, 1.5 parts of fucus extract, 0.15 parts of glycerin, 10 parts of deionized water, 0.2 parts of antimicrobial peptide

[0044] Preparation Process:

[0045] (1) Select fucus, kelp and wakame, then select and clean each raw material, remove thick stems and silt, filter the water, and pulverize each raw material with a pulverizer.

[0046] (2) Preparation of strain fermentation broth

[0047] Inoculate the Trichoderma reesei strain into common mold culture medium, and culture it on a shaker at 30°C and 150rpm for 6 days. When the mold content reaches 10 9 Above cfu / ml, stop fermentation and reserve;

[0048] (3) fermentation

[0049] Add the pulverized Fucus or Kelpia Kelp or Wakame into the fermenter, add 5 to 10 times of water, and then add (NH 4 ) 2 SO 4 0.2%, MgSO 4 0.15%, KH 2 PO 4 1%, peptone 1%, after stirring evenly, adjust the pH between 5.4 and 5.6, a...

Embodiment 3

[0055] Recipe: 4.5 parts of ribose (fermentation source), 5 parts of kelp extract, 5 parts of wakame extract, 5 parts of fucus extract, 4 parts of glycerin, 15 parts of deionized water, 0.6 parts of antibacterial peptide

[0056] Preparation Process:

[0057] (1) Select fucus, kelp and wakame, then select and clean each raw material, remove thick stems and silt, filter the water, and pulverize each raw material with a pulverizer.

[0058] (2) Preparation of strain fermentation broth

[0059] Inoculate the Trichoderma konshii strain in common mold culture medium, and culture it on a shaker at 30°C and 180rpm for 6 days. When the mold content reaches 10 9 Above cfu / ml, stop fermentation and reserve;

[0060] (3) fermentation

[0061] Add pulverized Fucus or Kelpia Kelp or Undaria pinnatifida into the fermenter, add 8 times of water, then add (NH 4 ) 2 SO 4 0.2%, MgSO 4 0.15%, KH 2 PO 4 2%, peptone 2%, after stirring evenly, adjust the pH between 5.4 and 5.6, after steam...

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PUM

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Abstract

The invention discloses a composition with the effects of exciting skin cell energy and repairing a skin barrier as well as a preparation method and an application of the composition, and belongs to the technical field of skin care and beauty. According to the invention, high-quality raw material is carefully selected, marine essence is extracted by adopting an advanced microbial fermentation technology, and scientific compatibility and synergistic interaction are realized; the composition has the effects of stimulating ATP synthesis of skin cells, activating cells, optimizing metabolism of the skin cells, helping to repair cell damage, increasing skin elasticity, relieving or preventing fine wrinkles and wrinkles, endowing skin with new vitality, forming a moisturizing protective film onthe surface layer of the skin, repairing a skin barrier, resisting skin dryness, helping the skin to replenish and lock water, and continuously moisturizing the skin; meanwhile, the effects of promoting skin oxidation resistance, scavenging free radicals, enhancing the defense capability of the skin to environmental pollution and the like are facilitated. The natural seaweed essence is perfectly fused with biotechnological functional components, does not contain any hormone, does not generate side effects, can be used for a long time, and can be widely applied to moisturizing and repairing products or anti-aging products.

Description

technical field [0001] The invention belongs to the technical field of skin care and beauty, and specifically relates to a composition with the functions of stimulating skin cell energy and repairing skin barrier, its preparation method and application. Background technique [0002] The skin is composed of three parts: epidermis, dermis and subcutaneous tissue. The skin of the human body is a natural barrier to protect the human body. It protects various tissues and organs of the human body from the invasion of pathogenic microorganisms and other external substances and physical and other mechanical damage, and prevents the loss of water, electrolytes and nutrients in the human body. The skin barrier is mainly composed of the sebum membrane of the epidermis and the stratum corneum. Damage to the skin barrier will cause imperfect repair of the skin's own system, and increase the loss of water through the epidermis, thereby affecting the living environment of skin cells, dest...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/34A61K8/60A61K8/64A61K8/9711A61Q5/02A61Q5/12A61Q19/00A61Q19/08
CPCA61K8/60A61K8/9711A61K8/345A61K8/64A61Q19/00A61Q19/08A61Q5/02A61Q5/12
Inventor 刘春辉李自托
Owner 北京皓尔生物科技有限公司
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