Quick-molding self-healing hydrogel and preparation method thereof

A hydrogel and self-healing technology, applied in the field of rapid prototyping self-healing hydrogel and its preparation, can solve the limitations of hydrogel mechanical strength and self-healing ability, hydrogel toxicity, and self-healing efficiency Advanced problems, to achieve the effect of improving self-healing performance, improving mechanical properties, and overcoming irreversibility

Active Publication Date: 2020-07-10
北京昊坤康源医疗科学技术发展有限责任公司
View PDF7 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the disadvantage of this method is that the freeze-thaw method has the disadvantages of long time consumption and many steps in the preparation process, and the mechanical strength and self-healing ability of the hydrogel are limited to a certain extent.
However, the disadvantages of this method are: there is a long time-consuming gel formation process, the defect of low healing efficiency, and the chemical cross-linking agent used in the preparation method will produce certain toxicity to the hydrogel, making it difficult to apply limited range
[0007] That is, in the prior art, the prepared PVA hydrogel has the defects of long gel time, poor mechanical properties, rapid prototyping and high self-healing efficiency.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Quick-molding self-healing hydrogel and preparation method thereof
  • Quick-molding self-healing hydrogel and preparation method thereof
  • Quick-molding self-healing hydrogel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0037] The present invention provides a kind of preparation method of rapidly forming self-healing hydrogel, comprising the following steps:

[0038] S1. Uniformly disperse polyvinyl alcohol powder in an aprotic solvent according to a preset mass volume ratio to obtain a polyvinyl alcohol solution; then, add a predetermined amount of catalyst to the polyvinyl alcohol solution until it is completely dissolved, and then add a predetermined amount The glycidyl methacrylate is stirred evenly, and reacted at 40-60°C for 4-8 hours; finally, precipitation is precipitated and vacuum-dried to obtain methacrylated polyvinyl alcohol;

[0039] S2. Disperse the methacrylylated polyvinyl alcohol obtained in step S1 in an aprotic solvent according to a preset mass-volume ratio, and fully stir until completely dissolved at 30-50° C. to obtain methacrylated polyethylene Alcohol solution; then, add a predetermined amount of succinic anhydride into the methacrylated polyvinyl alcohol solution, s...

Embodiment 1

[0057] A method for preparing a rapid-forming self-healing hydrogel, comprising the steps of:

[0058] S1, the preparation of methacrylylated polyvinyl alcohol:

[0059] Disperse 5 g of polyvinyl alcohol (PVA) powder in 100 mL of dimethyl sulfoxide, stir well at room temperature to obtain a polyvinyl alcohol solution, then add 0.11 g of p-dimethylaminopyridine (DMAP) catalyst, and continue stirring to completely dissolve it. Add 0.32g of glycidyl methacrylate (GMA) to the above polyvinyl alcohol solution, stir for 30min, react at 60°C for 6h, finish the reaction and drop to room temperature, then add a large amount of anhydrous acetone to the above solution, collect A precipitate precipitated out. The precipitate was dried under vacuum at room temperature to obtain methacrylylated polyvinyl alcohol.

[0060] S2, the preparation of carboxylated methacryl polyvinyl alcohol:

[0061] Take 3g of methacrylated polyvinyl alcohol prepared in step S1, disperse it in 90mL of dimethy...

Embodiment 2

[0070] The difference from Example 1 is that 1.2g of carboxylated methacryl polyvinyl alcohol is dissolved in 10mL of deionized water to prepare a precursor solution with a mass volume concentration of 12%, and add it to the precursor solution Add 0.01g 2-hydroxyl-4'-(2-hydroxyethoxy)-2-methylpropiophenone photoinitiator, all the other steps are the same as in Example 1, and Example 2 prepares a physical and chemical double network cross-linked Self-healing hydrogel named 12% PVA-GMA-COOH / Fe 3+ gel.

[0071] see image 3 Shown, the 12%PVA-GMA-COOH / Fe that embodiment 2 prepares 3+ 10%PVA-GMA-COOH / Fe prepared by the storage modulus and loss modulus ratio of the gel in Example 1 3+ The high concentration of the gel, which is due to the higher concentration of PVA-GMA-COOH, leads to a higher content of carboxyl groups and double bonds in the mixed solution, forming a denser cross-linked network structure, therefore, improving the strength of the hydrogel.

[0072] see Figure...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
wavelengthaaaaaaaaaa
diameteraaaaaaaaaa
Login to view more

Abstract

The invention provides a quick-molding self-healing hydrogel and a preparation method thereof. The preparation method comprises the following steps: by taking polyvinyl alcohol as a raw material, firstly, reacting the polyvinyl alcohol with glycidyl methacrylate to synthesize methacrylated polyvinyl alcohol, and then, carrying out esterification reaction on carboxyl on succinic anhydride and hydroxyl on the methacrylated polyvinyl alcohol to prepare carboxylated methacrylated polyvinyl alcohol; preparing a precursor mixed solution, mixing the precursor mixed solution with an iron tartrate solution containing ferric ions, and carrying out ultraviolet polymerization molding to prepare the quick-molding self-healing hydrogel with a physicochemical double-crosslinked single-network structure.The hydrogel has the advantages of being high in forming speed and excellent in self-healing performance, and has excellent mechanical properties.

Description

technical field [0001] The invention relates to the field of hydrogel material preparation, in particular to a rapid-forming self-healing hydrogel and a preparation method thereof. Background technique [0002] Hydrogel is a water-insoluble polymer material with a three-dimensional molecular network structure. Its molecular network is rich in hydrophobic groups and hydrophilic groups, which can absorb a large proportion of water in an aqueous environment and has a stable water retention. The good biocompatibility of hydrogel makes it widely used in tissue engineering, drug release, wound healing and other fields. At present, due to the vigorous development of the smart electronics industry, electronic equipment is required to withstand deformations such as folding, stretching, and twisting, and higher requirements are placed on the mechanical properties and fatigue resistance of materials. Therefore, hydrogel materials are receiving more and more attention. more and more a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C08J3/075C08J3/28C08L29/04C08K5/098C08F8/00C08F8/10C08F116/06
CPCC08J3/075C08J3/28C08F8/00C08F8/10C08J2329/04C08K5/098C08F116/06
Inventor 周应山张梦帆万婷婷刘欣杨红军顾绍金叶德展陶咏真徐卫林
Owner 北京昊坤康源医疗科学技术发展有限责任公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap