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Novel non-rigid image registration method

An image registration, non-rigid technology, applied in the field of image processing, can solve unreasonable problems and achieve effective registration effect

Active Publication Date: 2020-07-17
NANJING UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This is unreasonable, because the two components of the displacement field should be physically coupled

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0104] This example is to register a pair of artificial images, such as figure 2 As shown, (a) is a fixed image, (b) is a floating image, (c) is the DiffeoDemon model registration result, (d) is the VTV model registration result, (e) is the BD registration result, (f) is Registration results of the BGD model of the present invention.

[0105] From figure 1 As can be seen in the figure, the registration result obtained by the DiffeoDemons model is obviously too smooth, and the smear effect is relatively heavy. The registration results of the VTV model have obvious jagged edges. This example shows that the BGD model can register images with sharp edges and large grayscale variations.

[0106] Furthermore, in order to compare different non-rigid registration models, we use some well-recognized and effective evaluation indicators to evaluate the registration results of each model. Here we use the classic average structural similarity mSSIM, normalized mutual information (NMI)...

example 2

[0111] In this example, the non-rigid medical image registration BGDSSD model based on the bounded generalized deformation function is applied to the registration of liver CT images, such as image 3 As shown, (a) is a fixed image, (b) is a floating image, (c) is the DiffeoDemon model registration result, (d) is the VTV model registration result, (e) is the BD registration result, (f) is Registration results of the BGD model of the present invention.

[0112] Table 2 is from the average structure similarity mSSIM, normalized mutual information (NMI) and normalized cross-correlation coefficient (NCC) three quantitative indexes for embodiment 1 respectively in DiffeoDemons model, VTV model, BD model and the present invention The registration results under the BGD model are compared, and the optimal value is bolded. Table 2 illustrates the effectiveness of the BGD model of the present invention.

[0113] Table 2 Quantitative indicators of liver CT image registration results

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example 3

[0116] This example tests the BGD registration model of the present invention on two 3-dimensional public datasets. These two datasets are 3D lung CT image sequences, called 4D-CT and COPDgene datasets, respectively.

[0117] The 4D-CT dataset contains lung CT images of 10 different test subjects, and each test subject has 3D volume data at 10 different moments. Along the x-y-z direction, the average voxel resolution of the volume data of the first 5 testers is 1.1×1.1×2.5mm 3 , the average number of voxels is 256×256×103. Along the x-y-z direction, the average voxel resolution of the 3D volume data of the last 5 testers is 0.97×0.97×2.5mm 3 , the average number of voxels is 512×512×128 (see https: / / www.dir-lab.com / ReferenceData.html for detailed introduction). The 3D image in the exhalation phase and the 3D image in the inhalation phase are respectively used as a fixed image and a floating image. The image grayscale of this dataset is roughly in the range of [0,4000]. Th...

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Abstract

The invention discloses a novel non-rigid image registration method, which comprises the following steps of: constructing a second-order bounded generalized deformation function of a displacement field between a floating image and a fixed image, and taking the second-order generalized deformation function of the displacement field as a regular term of a variation model; according to the gray scaledistribution characteristics between the images to be registered, adopting different data items: when the gray level distribution between the images to be registered is close and local gray level offset does not exist, adopting the sum of square differences (SSD) as the data item of the model, and establishing a BGDSSD registration model; establishing a BGDLCC registration model by taking a localcorrelation coefficient (LCC) as a data item of the model when local gray scale offset exists between images to be registered; and solving the registration model by using an adaptive primal-dual algorithm to obtain a registration result. According to the invention, a smoother displacement field can be obtained on the premise of meeting bounded deformation, so that a more effective registration result is obtained.

Description

technical field [0001] The invention relates to the technical field of image processing, in particular to a non-rigid image registration method. Background technique [0002] Image registration is a technique widely used in the fields of computer vision and medical image processing and analysis. In a general sense, registration refers to corresponding some or all points in two or more images so that they all correspond to the same point of the imaging object. Therefore, the essence of image registration is to find a spatial geometric transformation between two or more images. The geometric transformation involved in image registration includes rigid body transformation, affine transformation, projective transformation and non-rigid transformation. The first three transformations are the overall transformation of the image, that is, the transformation parameters of each point in the image are consistent, while the non-rigid transformation allows the transformation parameter...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T7/33G06K9/62
CPCG06T7/344G06T2207/10081G06T2207/30056G06F18/22
Inventor 杨孝平聂梓伟刘海蓉李晨
Owner NANJING UNIV