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Disinfection preparation capable of rapidly damaging virus envelope

A disinfectant preparation and disinfectant technology, applied in the direction of disinfectants, antiviral agents, skin care preparations, etc., can solve the problem of no selection of drug resistance and achieve a strong effect of stability

Inactive Publication Date: 2020-08-21
武汉齿欣生物医药科技有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, this study proves that cetylpyridinium chloride can directly kill the virus by destroying the virus envelope, and there is no sign of selective drug resistance

Method used

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  • Disinfection preparation capable of rapidly damaging virus envelope
  • Disinfection preparation capable of rapidly damaging virus envelope
  • Disinfection preparation capable of rapidly damaging virus envelope

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] A mouthwash disinfectant that quickly damages the viral envelope, comprising the following components in weight percent:

[0041] Cetyl pyridinium chloride is preferably 0.1wt%;

[0042] Citric acid is preferably 0.0125wt%;

[0043] Sodium benzoate is preferably 0.1wt%;

[0044] Potassium sorbate is preferably 0.04wt%;

[0045] Glycerol is preferably 5wt%;

[0046] Sorbitol is preferably 5wt%;

[0047] Zinc gluconate is preferably 0.2wt%;

[0048] and water balance.

Embodiment 2

[0050] A kind of nasal washing disinfectant that is used to quickly damage the virus envelope, comprising the following components by weight percentage:

[0051] Cetyl pyridinium chloride is preferably 0.1wt%;

[0052] Citric acid is preferably 0.0125wt%;

[0053] Sodium benzoate is preferably 0.1wt%;

[0054] Potassium sorbate is preferably 0.04wt%;

[0055] Glycerol is preferably 5wt%;

[0056] and water balance.

Embodiment 3

[0058] A nasal washing and disinfection dry powder preparation for rapidly damaging viral envelopes, which comprises the following components by weight percentage:

[0059] Cetyl pyridinium chloride is preferably 0.1wt%;

[0060] Citric acid is preferably 0.0125wt%;

[0061] Sodium benzoate is preferably 0.1wt%;

[0062] Potassium sorbate is preferably 0.04wt%;

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Abstract

The invention discloses a disinfection preparation capable of rapidly damaging a virus envelope. According to the disinfection preparation, edible acid and cetylpyridinium chloride are used as main effective components, virus envelopes can be damaged in an extremely short time, then various envelop viruses can be rapidly killed; meanwhile, the disinfection preparation can also play a role in killing and inhibiting bacteria and fungi. According to different additives, the disinfection preparation can be divided into an in-vitro skin disinfection preparation (such as a hand disinfection solution) and an in-vivo mucous membrane disinfection preparation (such as mouthwash and nasal wash). According to different requirements, the disinfection preparation can also be processed into liquid and dry powder. The disinfection preparation disclosed by the invention has a rapid and efficient killing effect on various envelope viruses, bacteria and fungi. Besides, the disinfection preparation has the advantage of strong stability, has no stimulation to human skin, has no residue after use, is easily dissolved in water, is safe, has no toxic or side effect, and is suitable for disinfection of daily supplies such as mouth and nose mucosa, hand and foot skin, wounds, clothes and the like.

Description

technical field [0001] The invention relates to the technical field of disinfection, in particular to a disinfection preparation for rapidly damaging virus capsules. Background technique [0002] Viruses are a type of non-cellular organisms. A typical virus is composed of nucleic acid and its outer protein shell, but some virions have an envelope structure outside. This virus is called an enveloped virus. The capsule is mainly derived from the host cell membrane, which is a lipid bilayer membrane composed of proteins, polysaccharides and lipids. The protein molecules on the viral envelope are encoded by the viral genome, often in the form of glycoproteins or lipoproteins, which can mediate the fusion of the viral envelope with the host cell membrane or endosomal membrane, allowing the release of the viral contents into the host cell. The envelope also has the function of maintaining the structural integrity of the virion. Human acquired immunodeficiency syndrome virus (HIV...

Claims

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Application Information

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IPC IPC(8): A61K31/4425A61K9/08A61K9/14A61K47/12A61P17/00A61P31/02A61P1/02A61P11/02A61P17/02A61P31/18A61P31/20A61P1/16A61P31/16A61P31/14A61P31/04A61P31/10A61K8/49A61K8/365A61Q19/10A61Q17/00A61Q11/00A01N43/40A01P1/00A01P3/00
CPCA01N43/40A61K8/365A61K8/4926A61K9/0014A61K9/08A61K9/14A61K31/4425A61K47/12A61Q11/00A61Q17/005A61Q19/10A61P1/02A61P1/16A61P11/02A61P17/00A61P17/02A61P31/02A61P31/04A61P31/10A61P31/14A61P31/16A61P31/18A61P31/20
Inventor 张鹏陈甦明
Owner 武汉齿欣生物医药科技有限责任公司
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