Acne-removing composition as well as preparation method and application thereof
A composition and an acne-removing technology, which are applied in the directions of drug combinations, pharmaceutical formulations, cosmetic preparations, etc., can solve the problems of difficulty in achieving instant acne-removing, poor penetration of acne-removing products, insufficient mildness and safety, and the like, and improve the skin. Uncomfortable state, satisfying mass production, mild and safe formula
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[0079] Further, the second aspect of the present invention also provides a preparation method of the acne-removing patch, which includes the step of mixing the components of the acne-removing patch.
[0080] In particular, the present invention also provides a method for preparing a liquid anti-acne patch. The preparation method of the liquid anti-acne patch includes the following steps:
[0081] After mixing the film-forming agent and auxiliary materials, the premix is obtained;
[0082] The premix is mixed with the acne-removing composition of the first aspect to obtain a liquid acne-removing patch.
[0083] Furthermore, for the premix, after mixing the film-forming agent and auxiliary materials uniformly, heat to 75-85°C and keep the temperature for 10-20min to obtain a fully dissolved premix.
[0084] Specifically, after the pre-dispersed and dissolved film-forming agent and auxiliary materials are mixed evenly, the mixture is heated to 75-85° C. and kept for 10-20 mi...
Embodiment 1
[0091] In terms of parts by mass, the amount of 4-hydroxyethylpiperazineethanesulfonic acid added is 2 parts, the amount of salicylic acid derivatives added is 4 parts, and the mass ratio of salicylic acid and gum arabic is 1:1-1.25 , the addition of madecassoside is 0.4 parts, and the addition of PCA-Zn is 0.3 parts; 4-hydroxyethylpiperazineethanesulfonic acid, salicylic acid derivatives, madecassoside and PCA-Zn The mass ratio is 1:2:0.2:0.15.
[0092] Mix 4-hydroxyethylpiperazineethanesulfonic acid, salicylic acid derivatives, madecassoside and active zinc uniformly at room temperature to prepare acne-removing composition I.
Embodiment 2
[0094] In terms of parts by mass, the amount of 4-hydroxyethylpiperazineethanesulfonic acid added is 1 part, the amount of salicylic acid derivatives added is 1 part, and the mass ratio of salicylic acid and gum arabic is 1:1-1.25 , the addition of madecassoside is 0.2 parts, and the addition of PCA-Zn is 0.2 parts; 4-hydroxyethylpiperazineethanesulfonic acid, salicylic acid derivatives, madecassoside and PCA-Zn The mass ratio is 1:1:0.2:0.2;
[0095] Acne-removing composition II was prepared according to the preparation method in Example 1.
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