148 results about "Salicylic acid derivatives" patented technology

An object of the present invention is to provide a toner in which a charging amount and rise of the charging amount are hardly influenced by change in a temperature and humidity environment, and pigment dispersibility is high in order to provide an image output having high transparency, color mixing properties, and color nuance stability. The present invention is a toner comprising toner particles each comprising a metallic compound and a colorant, wherein the metallic compound is a compound having a structure bonded to a metal in a site derived from —COOM¹ and/or —OH of a salicylic acid structural moiety or a salicylic acid derivative structural moiety of an aromatic compound represented by formula (1) below:

A toner is provided that contains: (A) a binder resin; (B) a colorant; (C) a charge controlling agent; and (D) an additive; wherein the binder resin (A) contains:

• • a polyester resin containing no tetrahydrofuran-insoluble component; and having a molecular weight distribution wherein components having a molecular weight not greater than 5×10² are present in an amount of 4% or less by weight, and wherein a main peak is present in a molecular weight range of from 3×10³ to 9×10³ when the molecular weight distribution is determined by gel permeation chromatography; wherein the charge controlling agent (C) contains: a metal salt of salicylic acid or salicylic acid derivative; and wherein the additive (D) contains: a hydrophobized silica having a primary particle diameter of from 0.01 to 0.03 μm; and
  • a hydrophobized titanium oxide having a primary particle diameter of from 0.01 to 0.03 μm and a specific surface area of from 60 to 140 m²/g, wherein the hydrophobized titanium oxide is prepared by surface-treating a particulate titanium oxide prepared by a wet process, wherein the hydrophobized titanium dioxide has one or more water-soluble components in an amount of 0.2% or more by weight, and has a transmittance not less than 35% for light having a wavelength of 300 nm and a transmittance not less than 80% for light having a wavelength of 600 nm; and its use in a developer, an image forming method, image forming apparatus and a process cartridge containing the toner.

The present invention provides pharmaceutically acceptable salts having local anesthetic and anti-inflammatory activities. The preferred pharmaceutically acceptable salt is a diclofenac salt of lidocaine. Diclofenac is a non-steroidal anti-inflammatory drug (“NSAID”). Lidocaine is a local anesthetic. Other NSAID (except the salicylic acid derivatives of NSAID) can be used to replace diclofenac and/or other local anesthetics can be used to replace lidocaine. The pharmaceutically acceptable salts are crystalline compounds, which are distinctively different from either the NSAID alone or the local anesthetic alone, as indicated by differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), High Performance Liquid Chromatography (HPLC) and Fourier-Transformed Infrared Spectroscopy (FTIR) analyses. These pharmaceutically acceptable salts are suitable for use in topical treatment or parenteral injection to treat patients with localized pain, including muscle pain, joint pain, pain associated with herpes infection, and wound pain (such as surgical wound, burn wound etc.).

To obtain a resin for toners, or a toner, which is superior in the quickness in its rise of charging to a sufficient charge quantity in a short time, in the stability of charging that extends from the initial stage up to the printing on a large number of sheets, and in the stability of charging that comes in a high-temperature and high-humidity environment. As a charge control resin, it is characterized by containing a specific unit having sulfonic acid or a sulfonate as a substituent and a specific unit having a salicylic acid derivative.

Cosmetic composition containing, in an anhydrous medium, at least one exothermic metal salt, at least one carboxylic acid and at least one salicylic acid compound, chosen from salicylic acid and salicylic acid derivatives. The composition may be used in particular for cleansing and/or removing makeup from and/or scrubbing the skin.

Halosalicylic acid compounds of the present invention, having at least one halogen substituent on the aromatic ring, are employed to produce desquamation of skin, treat nail disorders or dandruff, remove calluses, control acne and excess sebum production, reduce skin pore size or control blackheads. Topical compositions containing the halosalicylic acid compound and a cosmetically acceptable vehicle are disclosed.

The invention discloses a overall-efficiency oil-controlling acne-removing pockmark-eliminating skin-beautifying essence. The essence comprises, by weight, 0.1 to 2% of extract of wild soybean seeds, 0.5 to 3% of extract of cordate houttuynia, 1 to 5% of extract of cortex phellodendron, 0.1 to 1% of extract of dragon's blood, 5 to 20 ppm of a salicylic acid derivative, 1 to 5% of glycerin, 0.5 to 10% of butylene glycol, 1 to 3% of hydroxyethylcarbamide, 0.5 to 2% of betaine and 0.5 to 3% of auxiliary components, with the balance being deionized water. According to the invention, through perfect combination of the extract of wild soybean seeds, the extract of cordate houttuynia, the extract of cortex phellodendron, the extract of dragon's blood and the salicylic acid derivative, the overall-efficiency oil-controlling acne-removing pockmark-eliminating skin-beautifying essence has overall effects of aiding the skin in continuous oil control, unblocking and astringing pores, removing acne, eliminating pockmarks, smoothing the skin, etc.

The invention provides a method for preparing a beta-amino-carbonyl compound. Aldehydes, ketones and amines are directly mixed under the condition of synergetic catalysis of titanocene dichloride and a ligand, and react at room temperature to obtain the beta-amino-carbonyl compound, wherein the ligand is salicylic acid or salicylic acid derivatives or structural analogues thereof. According to the method, the catalyst used in the method is low in cost, nontoxic and stable and effective to air and water, the reaction condition is mild, a solvent is not needed, the operation is simple, and the atom economy is high.

A production method for a full-color toner for electrophotography includes melt-kneading a toner material by use of an open-roll kneader, the toner material containing at least a binder resin, a wax, a colorant, and a charge control agent, wherein Mze/Mzi is 0.3 to 0.7, where Mze is a Z-average molecular weight of a resin component of the toner material to be supplied in the open-roll kneader, and Mzi is a Z-average molecular weight of a resin component of a kneaded product to be discharged from the open-roll kneader, and wherein a zirconium compound of a salicylic acid derivative is used as the charge control agent.

The invention provides hydroxyl-containing benzimidazole diamines and a preparation method thereof. The hydroxyl-containing benzimidazole diamines possess the structures shown as a formula (I), a formula (II) or a formula (III). The preparation method comprises the following steps: A1) reacting 1,2,4-benzenetriamine dihydrochloride with a salicylic acid derivative with the structure shown as a formula (IV), so as to obtain a hydroxyl-containing benzimidazole diamine with the structure shown as a formula (I); or A2) reacting 1,2,4-benzenetriamine dihydrochloride with a salicylic acid derivative with the structure shown as a formula (V), so as to obtain a hydroxyl-containing benzimidazole diamine with the structure shown as a formula (II); or A3) reacting 3,3'-diaminobenzidine with a salicylic acid derivative with the structure shown as a formula (IV), so as to obtain a hydroxyl-containing benzimidazole diamine with the structure shown as a formula (III). Compared with the prior art, polyimides prepared from the provided hydroxyl-containing benzimidazole diamines are high in strength and large in modulus.

The invention relates to a dispersant used for salicylic acid derivative pigments, a preparation method and the application thereof; the dispersant has the structures of formula (I), (II) and (III) and is liquid; wherein, the matrix is salicylic acid (ortho-hydroxy benzoic acid), linking group is amine methyl-CH2NH-, and solvated chain R is alkylene oxide polymer; the preparation method comprises the following steps: polyether primary amine and the salicylic acid are heated, stirred fully and evenly, and dipped with formaldehyde solution slowly, and the amine methylating product of the salicylic acid is prepared by Mannich reaction; the application thereof lies in improving the dispersibility of lake or disazo pigments used for solvent or water-based printing ink. The dispersant of the invention is colourless and improves the colour intensity of the pigments by virtue of synergistic action of the dispersant and the pigments; the printing ink produced by adding the pigments of the dispersant has higher colour intensity, transparency and low viscosity, and is applied widely.

The invention discloses a method for adsorbing and removing aluminum from rare earth material liquor through a complexing-ion exchange synergistic effect. Salicylic acid derivative is utilized as an organic ligand to treat a rare earth solution, then D290 type anion exchange resin is utilized to adsorb complexing anion generated by reaction between aluminum ions and the organic ligand, and aluminum ions can be removed from the material liquor. By means of controlling the organic ligand use amount, a reaction temperature, a solution pH value, the rare earth material liquor and a resin column flow velocity, a removal rate of aluminum ions in the rare earth material liquor can reach 70% or more, and rare earth loss does not exceed 5%. Compared with the prior art, the method for adsorbing andremoving aluminum from rare earth material liquor through the complexing-ion exchange synergistic effect has a low equipment requirement and simpleness in operation, and a lot of factory areas required by multilevel extraction of an extraction method are avoided; meanwhile, the problems that aluminum hydroxide flocculent precipitate is difficult to filter and has seriousness in entrainment; furthermore, the used D290 type anion exchange resin can be recycled, and production cost is reduced.

Hairy hoof warts in animals are treated by topically administering an effective amount of a composition of aspirin or other compound or derivative of salicylic acid that preferably contains at least 50% by weight and more preferably between about 75% and 100% by weight aspirin or other compound or derivative of salicylic acid. A preferred composition includes aspirin, hydrated lime, sodium bentonite, and chalk or iron oxide.

The present invention relates to novel compounds, compositions containing same and methods for inhibiting STAT3 and/or STAT5 activity or for the treatment of a STAT3 or STAT5-dependent cancer using said compounds; or a pharmaceutically acceptable salt, solvate or prodrug thereof.

The present invention provides a water-in-oil type that does not impair the function of the component in a system containing a salicylic acid derivative (alkoxysalicylic acid, etc.), has good emulsification stability over time, and is excellent in usability emulsified composition. The water-in-oil emulsified composition contains (a) a salicylic acid derivative (such as methoxysalicylate, ethoxysalicylate, etc.) and (b) in an aqueous phase (inner phase). ) salts, and (c) polyethylene glycol with a molecular weight of 1,000 to 200,000, and if necessary, the oil phase (external phase) contains 30% by mass or more of the oil phase (external phase) that is liquid at normal temperature silicone oil.

Provided is an electrophotographic photoconductor including: a conductive support; an undercoat layer; and a photoconductive layer, wherein the undercoat layer and the photoconductive layer are provided over the conductive support in the order of reciting, wherein the undercoat layer contains at least metal oxide particles, a binder, and a salicylic acid derivative such as 4-methylsalicylic acid, wherein the metal oxide particles have a volume resistivity of 1×10⁵ Ω·cm or higher but 1×10⁸ Ω·cm or lower, wherein the undercoat layer has a volume resistivity of 0.001×10⁶ Ω·cm or higher but 0.02×10⁶ Ω·cm or lower, and wherein the undercoat layer has a thickness of 2 micrometers or greater but 20 micrometers or less.

An electrophotographic toner comprising at least a fixing resin, a coloring agent, a release agent and a charge control agent, wherein the release agent is carnauba wax, the charge control agent is a boron complex of a salicyclic acid derivative, and the fixing resin contains two kinds of polyester resins in ratio represented by the following equation (1); $\begin{array}{cc}\frac{A\left(T_{1/2}\right)-A\left(T_{\mathrm{fb}}\right)}{B\left(T_{1/2}\right)-B\left(T_{\mathrm{fb}}\right)}\leqq \frac{A\left(T_{1/2}\right)\times C}{B\left(T_{1/2}\right)\times D}\leqq \frac{B\left(T_{1/2}\right)-B\left(T_{\mathrm{fb}}\right)}{A\left(T_{1/2}\right)-A\left(T_{\mathrm{fb}}\right)},& \left(1\right)\end{array}$

wherein in the above equation, A(T_1/2)−A(T_fb)<B(T_1/2)−B(T_fb), A(T_1/2) represents a softening point (° C.) of the polyester A, A(T_fb) a flow-out start point (° C.) of the polyester A, B(T_1/2) a softening point (° C.) of the polyester B, B(T_fb) a flow-out start point (° C.) of the polyester B, C a weight rate of the polyester A in the fixing resin, and D a weight rate of the polyester B in the fixing resin.