Acne-removing composition and its preparation method and application
A composition and anti-acne technology, which is applied in the direction of drug combinations, pharmaceutical formulas, cosmetic preparations, etc., can solve the problems of difficult to achieve instant anti-acne, poor penetration of anti-acne products, and insufficient mildness and safety, and achieve skin improvement. Uncomfortable state, satisfying mass production, mild and safe formula
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[0079] Further, the second aspect of the present invention also provides a method for preparing an acne-removing patch, which includes the step of mixing the components of the acne-removing patch.
[0080] In particular, the present invention also provides a preparation method of a liquid acne-removing patch, and the preparation method of the liquid acne-removing patch comprises the following steps:
[0081] The film-forming agent and the auxiliary materials are mixed for later use to obtain a premix;
[0082] The premix is mixed with the acne treatment composition of the first aspect to obtain a liquid acne treatment patch.
[0083] Further, for the premix, the film-forming agent and the auxiliary materials can be mixed uniformly, then heated to 75-85°C, and kept for 10-20min to obtain a fully dissolved premix.
[0084] Specifically, after uniformly mixing the pre-dispersed and dissolved film-forming agent and the auxiliary materials, it is heated to 75-85° C. and kept for...
Embodiment 1
[0091] In parts by mass, the addition of 4-hydroxyethylpiperazineethanesulfonic acid is 2 parts, the addition of salicylic acid derivatives is 4 parts, and the mass ratio of salicylic acid and gum arabic is 1:1~1.25 , the addition amount of madecassoside is 0.4 part, the addition amount of PCA-Zn is 0.3 part; The mass ratio is 1:2:0.2:0.15.
[0092] 4-Hydroxyethylpiperazineethanesulfonic acid, salicylic acid derivatives, madecassoside and active zinc are uniformly mixed at room temperature to prepare acne-removing composition I.
Embodiment 2
[0094] In parts by mass, the addition of 4-hydroxyethylpiperazineethanesulfonic acid is 1 part, the addition of salicylic acid derivative is 1 part, and the mass ratio of salicylic acid and gum arabic is 1:1~1.25 , the addition of madecassoside is 0.2 part, the addition of PCA-Zn is 0.2 part; the addition of 4-hydroxyethylpiperazineethanesulfonic acid, salicylic acid derivatives, madecassoside and PCA-Zn The mass ratio is 1:1:0.2:0.2;
[0095] According to the preparation method in Example 1, the anti-acne composition II was prepared.
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