Intestinal tract regulating type feed additive based on ulva lactuca polysaccharide dissolved out under high pressure as well as preparation method and application of intestinal tract regulating type feed additive

Abstract

The invention discloses an intestinal tract regulating type feed additive based on ulva lactuca polysaccharide dissolved out under high pressure as well as a preparation method and an application of the intestinal tract regulating type feed additive. Water-soluble polysaccharide of the feed additive accounts for 80% or above of the total sugar content; monosaccharide composition measured by a pre-column derivatization chromatography consists of rhamnose (25.0%, DW), xylose (6.0%, DW), glucuronic acid (9.0%, DW) and iduronic acid (3.1%, DW), wherein the sulfate group content is greater than 15%. The feed additive provided by the invention has a regulating effect on the intestinal health of weaned piglets, and the result shows that the product can effectively reduce the diarrhea rate of thepiglets and improve the feed-weight ratio of the piglets to a certain extent; the feed additive can improve the intestinal flora structure of piglets, inhibit the proliferation of intestinal harmful bacteria such as Mollicutes _ RF9 (flexible membrane bacteria), Escherichia-Shigella (Escherichia-Shigella) and Desulfovibrio (Desulfurization Vibrio) and the like, and promote the proliferation of bifidobacteria and clostridium butyricum; intestinal health of piglets is promoted, and intestinal inflammation is relieved; fermentation in the intestinal tract can promote the production of lactic acid, acetic acid, propionic acid and total SCFA.

Description

technical field [0001] The invention relates to a feed additive, in particular to a gut-regulating feed additive based on high-pressure dissolution of Ulva polysaccharide, a preparation method and application thereof. Background technique [0002] Gut flora plays an important role in inflammation, immunity and metabolic diseases, and is closely related to the health of its host. Diet is an important factor affecting the structure of gut flora, especially functional polysaccharides, which can be utilized by gut microbes , produces a large number of compounds through its metabolic activities, such as short-chain fatty acids (SCFA), which can be absorbed by the host and further metabolized as an energy source, and can also regulate the pH of the intestinal environment, maintain intestinal morphology and function, or serve as signaling molecules directly or indirectly affect the body's metabolism. [0003] Ulva lactuca (Ulva lactuca L.) is a large marine economical algae in the...

AI Technical Summary

Problems solved by technology

[0004] At present, the hot water (80-100°C) directly extracts Ulva polysaccharides, which takes a long time and has a low yield, and the extracted polysaccharides have low sulfate content; in order to increase the yield of sulfated polysaccharides, acid is currently used to reduce the pH ( 1-4) Extraction, but if the pH is too low, the sugar unit structure, especially the sulfate group, will be destroyed; when adding acid for degradation, the inevitable pH adjustment will also cause the problem of excessive salt concentration; and in order to obtain high-yield polysaccharides, It still needs a long extraction time, which will cause equipment loss (acid corrosion); there is another method is enzyme-assisted extraction, but the enzyme is expensive and must meet the enzyme’s action conditions such as temperature, pH, etc., and maintain a relatively high temperature. Long action time, and yield improvement is still limited

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