Composition for regulating and controlling epidermal micro-ecological balance and application thereof
A technology of ecological balance and composition, which is applied in the direction of drug combination, skin care preparations, medical preparations containing active ingredients, etc., can solve the problem of destroying the balance between probiotics and harmful bacteria, and achieve improvement of skin problems, excellent heat resistance Stability, long-term storage effect
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[0035] In some embodiments, the preparation method of the organic solvent extract comprises the steps of:
[0036] Patchouli leaves are crushed and added to the extraction tank, mixed with organic solvents, soaked for 2 to 4 hours, heated to 85°C for reflux extraction for 2 to 4 hours, then the system is cooled to room temperature, left standing to separate layers, and filtered to obtain the upper layer The clear liquid is obtained by concentrating and drying.
[0037] In some preferred embodiments, the mixed organic solvent is a mixture of methanol and ethyl acetate.
[0038] Preferably, the volume ratio of methanol to ethyl acetate is 1.5:1.
[0039] Further preferably, the solid-liquid ratio of the patchouli leaves and the mixed organic solvent is 1g: (40-60ml).
[0040] Even more preferably, the solid-liquid ratio of the patchouli leaves and the mixed organic solvent is 1g:55ml.
[0041] In some embodiments, the preparation method of the lye extract comprises the steps ...
Embodiment 1
[0063] Example 1 : present embodiment provides a kind of composition regulating epidermal micro-ecological balance, and its preparation raw material, by weight, comprises
[0064]
[0065] The plankton extract was purchased from Xiamen Xulijin Biotechnology Co., Ltd.; the inulin / α-glucan oligosaccharides (both purchased from Shanghai Merrill Chemical Technology Co., Ltd.) were inulin and α-glucan A mixture of oligosaccharides, the weight ratio is 1:1; the patchouli leaf extract includes organic solvent extract and lye extract, the weight ratio is 1.8:1; the preparation method of the organic solvent extract includes the following step:
[0066] Patchouli leaves are crushed and added to the extraction tank, mixed with organic solvents, soaked for 2.5 hours, heated to 85°C for reflux extraction for 3 hours, then cooled to room temperature, allowed to stand for layers, filtered to obtain the supernatant, concentrated Serve dry. The mixed organic solvent is methanol and ethyl...
Embodiment 2
[0071] Example 2 : present embodiment provides a kind of composition regulating epidermal micro-ecological balance, and its preparation raw material, by weight, comprises
[0072]
[0073] The plankton extract was purchased from Xiamen Xulijin Biotechnology Co., Ltd.; the inulin / α-glucan oligosaccharides (both purchased from Shanghai Merrill Chemical Technology Co., Ltd.) were inulin and α-glucan A mixture of oligosaccharides, the weight ratio is 1:1; the patchouli leaf extract includes organic solvent extract and lye extract, the weight ratio is 1.8:1; the preparation method of the organic solvent extract includes the following step:
[0074] Patchouli leaves are crushed and added to the extraction tank, mixed with organic solvents, soaked for 2.5 hours, heated to 85°C for reflux extraction for 3 hours, then cooled to room temperature, allowed to stand for layers, filtered to obtain the supernatant, concentrated Serve dry. The mixed organic solvent is methanol and ethy...
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