Step type microfluidic droplet or bubble emulsification module

A micro-droplet, stepped technology, applied in the field of microfluidics, can solve the problems of low channel activation and interference.

Active Publication Date: 2020-10-30
TIANJIN UNIV
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  • Abstract
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Problems solved by technology

[0007] In order to solve the problems in the prior art, the present invention provides a step-type microfluidic droplet or bubble emulsification module, which solves the problem that the activation degree of the channel in the step-type chip in the prior art is not high, and the downstream step channel is easily affected by the upstream during the emulsification process. Problems with generated droplet / bubble interference

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  • Step type microfluidic droplet or bubble emulsification module
  • Step type microfluidic droplet or bubble emulsification module
  • Step type microfluidic droplet or bubble emulsification module

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Embodiment Construction

[0030] The present invention will be described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0031] The structure of the stepped microfluidic droplet / bubble emulsification module of the present invention is as follows: figure 1 As shown, the dispersed phase enters the droplet / bubble emulsifier 4 in the droplet / bubble emulsification chamber 6 through the dispersed phase transportation pipeline 1 in the middle, the continuous phase enters the droplet / bubble emulsification chamber 6 through the continuous phase transportation pipeline 2, and the dispersed phase The droplet / bubble emulsification process is completed in the droplet / bubble emulsifier 4 to generate micro-droplets / bubbles. The droplet / bubble transport channel 5 is in communication with the droplet / bubble emulsification chamber 6, and the micro-droplets generated in the droplet emulsification chamber 6 and the continuous phase in the continuous phase transport pipeline 2 flow...

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Abstract

The invention discloses a step type microfluidic droplet or bubble emulsification module. The module comprises an upper dispersed phase and continuous phase conveying pipeline, a middle droplet / bubbleemulsifying cavity and a lower micro droplet / bubble conveying channel. A plurality of disc-shaped stepped liquid drop / bubble emulsifiers are arranged in the liquid drop / bubble emulsifying cavity. A plurality of wedge-shaped divergent step channels are uniformly distributed at the edges of the disc-shaped emulsifiers in an annular array manner. In the droplet and bubble production process, conversion of the production working condition can be achieved only by switching of the module placement direction needs. The droplet / bubble emulsification module can effectively solve the problems that theactivation degree of part of channels in a stepped chip is not high after the number of the channels is increased, and downstream stepped channels are easily interfered by upstream generated droplets / bubbles in the emulsification process.

Description

technical field [0001] The invention belongs to the field of microfluidic technology, in particular to a stepped microfluidic droplet or bubble emulsification module. Background technique [0002] As we all know, micro-droplets / bubbles are widely used in food emulsification, drug packaging, medical testing, functional particle preparation and other common high-tech applications due to their high specific surface area and the ability to isolate other substances and act as independent reaction units. technology field. In recent years, one of the main goals of the rapid development of microfluidic technology is to find better ways to produce micro-droplets / bubbles with controllable size and excellent monodispersity. [0003] With the continuous development of this technology, several commonly used configurations of microfluidic devices have emerged, represented by T-shaped, Y-shaped, flow-condensed, co-flow, and stepped microchannel structures. Compared with other traditional...

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Application Information

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IPC IPC(8): B01L3/00
CPCB01L3/5027
Inventor 刘子炜付涛涛马友光
Owner TIANJIN UNIV
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