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Application of cuminal in preparation of medicine for treating echinococcosis granulosa

A technology of echinococcosis and echinococcus granulosus, which is applied in the field of preparation of echinococcus granulosus in vitro inhibitors, and can solve the problems of low drug concentration in the liver and poor intestinal absorption

Pending Publication Date: 2020-11-13
THE FIRST TEACHING HOSPITAL OF XINJIANG MEDICAL UNIVERCITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the anti-hydatid drug recommended by WHO is albendazole (ABZ), but albendazole has the disadvantages of poor intestinal absorption and low liver drug concentration. In recent years, some scholars have devoted themselves to the research of new formulations of albendazole. Albendazole emulsion, albendazole liposome, albendazole chitosan and other dosage forms have been obtained, and pharmacodynamic studies have been carried out, and certain progress has been made, but for the prevention and treatment of echinococcosis, Finding new drugs and targets is still of great significance

Method used

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  • Application of cuminal in preparation of medicine for treating echinococcosis granulosa
  • Application of cuminal in preparation of medicine for treating echinococcosis granulosa
  • Application of cuminal in preparation of medicine for treating echinococcosis granulosa

Examples

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Embodiment 1

[0029] Example 1: Application of a kind of cuminaldehyde in the preparation of medicine for treating cystic echinococcosis.

Embodiment 2

[0030] Example 2: An application of cuminaldehyde in the preparation of a drug for treating echinococcosis.

Embodiment 3

[0031] Example 3: An application of cuminaldehyde in the preparation of an inhibitor of Echinococcus granulosus.

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Abstract

The invention relates to the technical field of cuminal pharmaceutical application, in particular to an application of cuminal in preparation of a medicine for treating echinococcosis granulosa. The invention discloses that cuminal has an inhibiting effect on echinococcus granulosus protoscolex for the first time, cuminal with different concentrations has certain inhibiting and killing effects onechinococcus granulosus protoscolex, and a new medicine is provided for treating echinococcus granulosus.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical use of cuminaldehyde, relates to the application of cuminaldehyde in the preparation of medicines for treating echinococcosis granulosus, and also includes the application of cuminaldehyde in the preparation of medicines for treating cystic echinococcosis , the application of cuminaldehyde in the preparation of inhibitors of Echinococcus granulosus and the application of cuminaldehyde in the preparation of in vitro inhibitors of Echinococcus granulosus. Background technique [0002] Echinococcus, also known as echinococcosis, is a zoonotic parasitic disease caused by the larvae of Echinococcus larvae parasitizing the human body, about 95% of which are Echinococcus granulosus (Eg) Cystic echinococcosis (CE) caused by infection. The disease is common in Europe, Russia, North America and the northwestern pastoral areas of my country, and is a serious public health problem of great concern. I...

Claims

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Application Information

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IPC IPC(8): A61K31/11A61P33/10
CPCA61K31/11A61P33/10
Inventor 文丽梅卢帅丁楠巩月红陈蓓张海波高惠静
Owner THE FIRST TEACHING HOSPITAL OF XINJIANG MEDICAL UNIVERCITY
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