A kind of trapping device and process for the production of o-chlorobenzonitrile

Abstract

The invention discloses a trapping device and process for production of o-chlorobenzonitrile. The device is simple and reasonable in structural design, high in implementation feasibility and high in practicability, 90% or above of ammonium chloride is captured through a first-stage catcher by a dry capture method, 70% or above of the o-chlorobenzonitrile is captured through a second-stage catcherby a dry capture method,, the first-stage catcher makes full use of latent heat of vaporization of water, and the usage amount of spray liquid-water is small. Besides, about 30% of crude o-chlorobenzonitrile products captured by a third-stage catcher and a fourth-stage catcher is molten with hot water, dehydrated, rectified and purified to obtain an o-chlorobenzonitrile liquid pure product, and the tar generation amount and the solid waste generation amount in the rectification process are small. Compared with a traditional multi-stage wet capture method, the loss amount of the o-chlorobenzonitrile is reduced. Besides, the investment cost of rectification equipment is reduced by more than half, the rectification energy consumption is equivalent to 30% of that of the traditional method, andthe economic benefits are good.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical synthesis, in particular to a trapping device and process for the production of o-chlorobenzonitrile. Background technique [0002] O-chlorobenzonitrile (CBN) is an important intermediate in organic synthesis, mainly used in the synthesis of dye intermediate 2-cyano-4-nitroaniline, and in the pharmaceutical industry for the synthesis of new antimalarial drug nitroquine and various anti-inflammatory and bactericidal drugs , for the preparation of non-peptide anti-angiotensin, etc., and can also be used for the preparation of important carbon steel corrosion inhibitors, etc. [0003] The production of 2-cyano-4-nitroaniline in my country is mainly used for the synthesis of disperse dyes and as a pesticide intermediate: o-chlorobenzonitrile can be nitrated and ammonolysis (aminated) to obtain 2-cyano-4-nitro Aniline, 2-cyano-4-nitroaniline is an important intermediate in the synthesis of dispe...

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Problems solved by technology

Chinese patents CN201384868 Y and CN101954231 B both adopt the trapping method of water spraying. The biggest problem of this trapping method is that the amount of wastewater to be treated is large, the cost of wastewater treatment is very high, and it is difficult to cool down the circulating spray water

At present, the domestic production of aromatics with nitrile groups and halogenated aromatics by the ammonia oxidation method is mainly thin-walled capture. This capture method is labor-intensive for workers and the working environment on site is harsh, and continuous discharge of products cannot be achieved. , a large amount of wastewater treatment

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