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Device for measuring related substances of edaravone injection by liquid chromatography

A technology of edaravone and liquid chromatography, which is applied in the field of devices for the determination of related substances of edaravone injection by liquid chromatography, can solve the problems of inconvenient use and inability to rotate, and achieve the effect of convenient use

Pending Publication Date: 2020-12-18
SINOPHARM GRP XINJIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] However, most of the existing liquid chromatographs are fixed on the table and cannot be rotated, which is inconvenient to use

Method used

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  • Device for measuring related substances of edaravone injection by liquid chromatography
  • Device for measuring related substances of edaravone injection by liquid chromatography
  • Device for measuring related substances of edaravone injection by liquid chromatography

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Embodiment Construction

[0019] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0020] see Figure 1~3 , in the embodiment of the present invention, the device for determining the related substances of Edaravone injection by liquid chromatography includes a housing 1, the bottom of the inner wall of the housing 1 is fixedly connected with a first motor 2, and the first motor 2 The shaft extension end of the shaft is fixedly connected with a rotating shaft 3, the outer wall of the rotating shaft 3 is movably sleeved with a sleeve 5, and th...

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Abstract

The invention discloses a device for measuring related substances of edaravone injection by liquid chromatography. The device comprises a shell, wherein a first motor is fixedly connected to the bottom of the inner wall of the shell; a rotating shaft is fixedly connected to the shaft extension end of the first motor; a sleeve is movably connected to the outer wall of the rotating shaft in a sleeving manner; a plurality of limiting grooves are formed in the outer wall of the rotating shaft; limiting strips are fixedly connected to the positions, corresponding to the limiting grooves, of the inner wall of the sleeve; the limiting strips are positioned in the corresponding limiting grooves; the top end of the sleeve penetrates through the inner wall of the shell and then is fixedly connectedwith a mounting plate; and a liquid chromatograph is arranged at the top of the mounting plate. According to the device disclosed by the invention, by arrangement of the first motor, the rotating shaft, the limiting grooves, the sleeve and the limiting strips, the first motor is utilized to drive the rotating shaft to rotate, and the sleeve can drive the mounting plate to rotate by matching and limiting of the limiting grooves and the limiting strips, so that rotation of the liquid chromatograph is realized and the liquid chromatograph is more convenient to use.

Description

technical field [0001] The invention relates to a liquid chromatograph, in particular to a device for determining related substances of Edaravone injection by liquid chromatography. Background technique [0002] Edaravone is a brain protectant (free radical scavenger). Clinical studies have shown that N-acetylaspartic acid (NAA) is a specific marker of surviving nerve cells, and its content decreases sharply in the early stage of cerebral infarction. The administration of edaravone to patients in the acute stage of cerebral infarction can inhibit the reduction of local cerebral blood flow around the infarction, and make the NAA content in the brain significantly higher than that of the glycerol control group on the 28th day after the onset. Preclinical studies suggest that intravenous administration of edaravone to rats after ischemia / ischemia-reperfusion can prevent the progression of cerebral edema and cerebral infarction, relieve the accompanying neurological symptoms, a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): F16M11/04F16M11/08F16M11/18F16M11/32G01N30/02
CPCF16M11/04F16M11/08F16M11/18F16M11/32G01N30/02
Inventor 倪爽爽王道玲高森焱姚雪
Owner SINOPHARM GRP XINJIANG PHARMA