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Plant fermentation product and preparation method and application thereof in stomach health care

A plant fermentation and plant extract technology, applied in the field of plant fermentation and its preparation, and stomach health care, can solve problems such as affecting health, unhealthy eating habits, affecting the quality of drinking life, etc., and achieve the effect of reducing inflammation and improving activity.

Inactive Publication Date: 2021-01-08
TCI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Especially modern people live at a fast-paced pace, coupled with unhealthy eating habits, it is easy to be associated with stomach problems, which not only affects health, but also affects the quality of drinking life

Method used

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  • Plant fermentation product and preparation method and application thereof in stomach health care
  • Plant fermentation product and preparation method and application thereof in stomach health care
  • Plant fermentation product and preparation method and application thereof in stomach health care

Examples

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preparation example Construction

[0034] The invention provides a plant fermented product and its preparation method and its use for stomach protection and health care. The plant fermented product of the present invention is prepared by mixing raspberry, yam, hawthorn and solvent in a ratio of 1-3:1-5:1:20- The ratio of 40 (w / w) is obtained by extracting at a specific time and temperature, first fermented with yeast and Lactobacillus plantarum, and then fermented with Acetobacter, wherein the yeast is a strain of BCRC20271, The Lactobacillus plantarum is a BCRC910805 strain, and the Acetobacter is a BCRC11688 strain. The plant fermented product of the present invention can effectively inhibit the growth of gastric Helicobacter pylori in vivo; reduce the expression levels of IL-1β gene, IL-23 gene, IL-12A gene, IL-3 gene, and TNF-α gene in gastric cells; And it can increase the expression of TGFβ gene.

[0035] At the same time, the composition for protecting the stomach and health care of the present inventio...

Embodiment 1

[0037] Embodiment 1 The preparation method of plant fermented product of the present invention

[0038] In one embodiment of the present invention, after mixing the radish seed, the tuber of yam, and the fruit of hawthorn in a weight percentage of 1-3:1-5:1-3, the mixture is mixed with water, alcohol, or a mixture of alcohol and water The extraction solvent is uniformly mixed at 3-11:20-40 weight percent, wherein the extraction solvent is preferably water, and after simultaneous sterilization and extraction at 50-100 ° C for 0.5-3 hours, the plant water extract is cooled to room temperature For the subsequent two-stage fermentation, the following three types of bacteria are used for the two-stage fermentation in sequence: yeast and Lactobacillus plantarum are co-cultured for fermentation, and then Acetobacter is used for fermentation. This fermentation sequence cannot be reversed, and its fermentation The time ratio is 1-5:3-15. In a preferred embodiment of the present invent...

Embodiment 2

[0039] Embodiment 2 Plant fermented product of the present invention inhibits the effect of gastric Helicobacter pylori growth

[0040] One embodiment of the present invention is to carry out the two-stage fermentation step of the present invention to improve the efficacy test of the plant fermented product inhibiting the growth of gastric Helicobacter pylori, and utilize the inhibition zone method to test its antibacterial efficacy, wherein the inhibition zone method is also called the diffusion method, It is a method of using the substance to be tested to diffuse in agarose gum to inhibit the growth of bacteria around it to form a transparent circle, that is, the zone of inhibition, and to determine the antibacterial effect of the substance to be tested according to the size of the zone of inhibition. It is often used in Isolation and screening of antibiotic-producing bacteria.

[0041] First, 1% gastric Helicobacter pylori (purchased from the Biological Resource Conservatio...

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Abstract

The invention relates to the field of plant fermentation, in particular to a plant fermentation product as well as a preparation method and application thereof in stomach health care. The invention discloses a plant fermentation product for stomach health care, which is prepared by the following steps: mixing radish seed, Chinese yam and hawthorn according to the weight percentage of 1-3: 1-5: 1-3to obtain a mixture, extracting with a solvent to obtain a plant extract, and fermenting to obtain the plant fermentation product. The plant fermentation product can effectively inhibit the growth ofhelicobacter pylori in the stomach and effectively reduce the expression quantity of IL-1beta genes, IL-23 genes, IL-12A genes, IL-3 genes and TNF-alpha genes which can promote inflammatory responsein gastric cells; the expression quantity of the TGF beta gene capable of inhibiting inflammatory reaction can be improved, so that the activity of resisting gastric pylori in vivo is improved, the inflammatory reaction of the stomach is reduced, and the effect of health care of the stomach is achieved.

Description

technical field [0001] The invention relates to the field of plant fermentation, in particular to a plant fermented product, its preparation method and its use for stomach health care. Background technique [0002] Inflammatory response is the defensive response of tissues in the vascular system to inflammatory factors and local damage. It is mainly a physiological response stimulated by trauma, bleeding, or pathogenic infection. It includes symptoms such as redness, fever, and pain. Inflammation is a protective measure of the innate immune system to remove harmful stimuli or pathogens and promote tissue repair. Usually, inflammation is beneficial. However, sometimes inflammation may cause an allergic reaction of the body's own immune system, which can lead to Allergic conditions of the immune system such as rheumatoid arthritis and lupus. Among them, steroids, non-steroidal anti-inflammatory drugs, and antihistamines are commonly used in medicine to suppress inflammation, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P1/00
CPCA61K2236/19A61K36/31A61K36/8945A61K36/734A61P1/00A61K2300/00A61K47/6911A61K9/127A61K45/06
Inventor 林咏翔庄伟秀
Owner TCI CO LTD
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