Vacuum ultraviolet light internal ionization mass spectrometry device and mass spectrometry method

Abstract

The invention provides a vacuum ultraviolet light internal ionization mass spectrometry device and a mass spectrometry method. The vacuum ultraviolet light internal ionization mass spectrometry devicecomprises an ultraviolet light source, a mass analyzer, a light beam adjusting part, an analysis sample and a controller; the ultraviolet light source can be used for carrying out single-photon ionization on an analysis sample; the mass analyzer can internally carry out a complete mass spectrum working time sequence from ionization of the analysis sample to ion mass separation; the mass analyzeris provided with a light source introduction port; the light beam adjusting part is arranged at the upstream of the light source introduction port; the controller can synchronously control the workingtime sequence stage of the mass analyzer and the modulation quantity of the light beam adjusting part; a simple valve or a light modulation structure is adopted, a high-sensitivity internal ionization analysis mode can be used in vacuum ultraviolet light ionization mass spectrometry, and meanwhile, bottom noise signal interference caused by a traditional continuous ultraviolet light source ionization method is avoided. And the analysis and detection limit can be improved by about 2-3 orders of magnitudes.

Description

technical field [0001] The invention relates to the technical field of mass spectrometry, in particular to a vacuum ultraviolet light internal ionization mass spectrometry device and a mass spectrometry method. In particular, it relates to a miniature mass spectrometer analysis device and method thereof which realize ionization of a sample to be measured and reduce interference in the mass analysis stage through a small continuous ultraviolet photoionization light source. Background technique [0002] Mass spectrometry is widely used in public security, biomedicine, advanced material analysis and development and other fields. Among them, small and micro mass spectrometry systems have gradually become important analysis methods in field analysis applications in various fields such as national defense security and other industrial and civil applications. At present, the portable on-site mass spectrometry analysis mainly relies on gas chromatography-mass spectrometry technolog...

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Problems solved by technology

[0006] Patent document CN1811408B proposes internal photoionization ion trap mass spectrometry for the analysis and detection of samples, but due to the difficulty in the stability of pulse generation of vacuum ultraviolet light, there is no micro-mass spectrometry that can really perform high-sensitivity internal ionization mode analysis. Apparatus and method thereof

[0007] The main reasons for this problem are: the instability of the light source in the sample ionization stage of the mass analyzer, and the strong background noise caused by the continuous ionization of the substances in the mass analyzer by the continuous input of vacuum ultraviolet light in the mass analysis stage

In fact, especially because the vacuum ultraviolet light input in the mass analysis stage cannot be stopped smoothly, the improvement of the relative sensitivity of mass spectrometry detection and the detection limit that should be brought about by the internal ionization method are basically impossible to achieve.

Therefore, it is necessary to find a miniature mass spectrometry device and analysis method that overcomes the timing control instability of vacuum ultraviolet light, improves the signal repeatability in the ionization stage of internal ionization mass spectrometry, and eliminates the photoionization background noise in the mass analysis stage.

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