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A treatment agent for reducing background luminescence value of immunodiagnostic reagents and preparation method thereof
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A technology of immunodiagnosis and treatment agent, which is applied in the field of treatment agent and its preparation for reducing the background luminescence value of immunodiagnostic reagents, and can solve the problems of high background luminescence value and reduction of background luminescence value of immunodiagnostic reagents, etc.
Active Publication Date: 2021-04-30
GUANGZHOU KEFEN BIOTECH CO LTD
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[0005] In order to overcome the deficiencies in the prior art, one of the purposes of the present invention is to provide a treatment agent that reduces the background luminescence value of immunodiagnostic reagents, which can effectively solve the problem of excessive background luminescence value in immunodiagnostic reagents, greatly improving The sensitivity and product quality of the product can meet the clinical requirements to reduce the occurrence of misdiagnosis
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Embodiment 1
[0030] A method for preparing a treatment agent for reducing the background luminescence value of an immunodiagnostic reagent, comprising the following preparation steps:
[0031] Add 0.05% tetramethylammonium chloride, 0.05% 2-bromoethyltrimethylammonium bromide, 0.1% Tween-20, 0.1% EDTA, 0.1% alkylbenzenesulfonate, 0.1 % alkyl sulfonate, 0.1% alkyl glyceryl ether sulfonate, after mixing, adjust the pH value to 6.3, that is.
Embodiment 2
[0033] A method for preparing a treatment agent for reducing the background luminescence value of an immunodiagnostic reagent, comprising the following preparation steps:
[0034] Add 0.1% tetramethylammonium chloride, 0.1% 2-bromoethyltrimethylammonium bromide, 0.1% Tween-20, 0.1% EDTA, 0.25% alkylbenzenesulfonate, 0.25 % alkyl sulfonate, 0.25% alkyl glyceryl ether sulfonate, after mixing, adjust the pH value to 6.3, that is.
Embodiment 3
[0036] A method for preparing a treatment agent for reducing the background luminescence value of an immunodiagnostic reagent, comprising the following preparation steps:
[0037] Add 0.2% tetramethylammonium chloride, 0.2% 2-bromoethyltrimethylammonium bromide, 0.1% Tween-20, 0.1% EDTA, 0.5% alkylbenzenesulfonate, 0.5 % alkyl sulfonate, 0.5% alkyl glyceryl ether sulfonate, after mixing, adjust the pH value to 6.3, that is.
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Abstract
The invention discloses a treatment agent for reducing the background luminescence value of immunodiagnostic reagents, which comprises the following components by mass: 0.05-0.4 parts of a catalyst; 0.1-1.5 parts of a surfactant; 0.1-0.2 parts of a chelating agent; 0.1-1.5 parts of acid salt compounds. The treatment agent of the present invention is applied to immunodiagnostic reagents, which can effectively solve the problem that the background luminescence value is too high and affect the accuracy of clinical low-concentration specimen measurement, greatly improve the sensitivity and product quality of the product, and can meet clinical requirements. Occurrence of misdiagnosis. The invention also provides a preparation method of a treatment agent for reducing the background luminescence value of the immunodiagnostic reagent.
Description
technical field [0001] The invention relates to the technical field of immunodiagnostic reagents, in particular to a treatment agent for reducing the background luminescence value of immunodiagnostic reagents and a preparation method thereof. Background technique [0002] Immunodiagnosis belongs to one subdivision of the field of in vitro diagnostic reagents. Immunodiagnosis is the application of immunological theories, techniques and methods to diagnose various diseases. Immunodiagnostic reagents have the most varieties in diagnostic kits, and are widely used in hospitals, blood stations, and physical examination centers, mainly for hepatitis testing, STD testing, tumor testing, pregnancy testing, etc. [0003] Immunodiagnosis includes radioimmunoassay, enzyme-linked immunoassay, chemiluminescence, etc. The immunodiagnostic detection method is a series of experimental methods for the determination of antigens and antibodies designed by applying the theory of immunology. T...
Claims
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