An entrainment-controlled flow-type supercritical extraction pharmaceutical equipment

Abstract

The invention discloses an entrainment flow control type supercritical extraction pharmaceutical equipment, which belongs to the technical field of pharmaceuticals. The invention can realize the innovative introduction of self-variable throwing balls to distribute powdery materials, and then use the mutual interaction of the entrainer itself Impact blending makes the entrainer split into smaller droplets, which is not only conducive to full mixing with the supercritical carbon dioxide fluid, but also more fully and effectively when in contact with the material. A jacking force of the self-variable throwing ball forces the self-variable throwing ball to rise a small distance, while the powdery material continues to rise under the action of inertia and stays in the air for a certain period of time under the action of buoyancy. At this time, the self-variable throwing ball is set. While transporting the mixed fluid, the self-shaking stick of the material transports the powdery material to be separated, so as to promote its further diffusion, so that it can fully contact with the mixed fluid to achieve efficient extraction, and greatly improve the extraction efficiency and effect of traditional Chinese medicine materials. .

Description

Technical field [0001] The present invention relates to the field of pharmaceutical techniques, and more particularly to an entry-controlled flow supercritical extraction pharmaceutical device. Background technique [0002] Supercritical is supercritical fluid, is a neutrically non-gaseous and non-liquid state, which can only exist when the temperature and pressure exceeds the critical point, and the density of supercritical fluid is more Large, similar to the liquid, and its viscosity is close to the gas, so supercritical fluid is a very ideal extractant. In the process of pharmaceutical, the supercritical extraction equipment will generally use the effective material of Chinese herbal medicine. Extraction, The principle of supercritical carbon dioxide fluid extraction separation process is to utilize the relationship between the dissolution of the supercritical fluid and its density, i.e., using pressure and temperature on the effect of supercritical fluid solubility. [0003] ...

AI Technical Summary

Problems solved by technology

[0005] The extraction rate of existing supercritical extraction devices generally depends on the extraction effect of the extraction tank and the separation effect of the separator. Due to the characteristics of supercritical fluid, it is easy to achieve a high separation rate from the operation of changing temperature and pressure, even Multi-stage separation and rectification are used to improve the separation effect, but most of the extraction kettles still use simple hanging baskets to hold the materials for static extraction. Due to the accumulation and limited space of the materials, it is difficult to carry out the separation process with the supercritical fluid. Sufficient contact leads to a low single-pass extraction rate. It is often necessary to use repeated extraction or continuous countercurrent extraction to increase the extraction rate of the material. The entrainer is simply mixed with the material or carbon dioxide, resulting in poor effect and greatly The extraction efficiency is reduced, and the extraction cost also increases

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