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Method of predicting gender by using blood marker

A technology of blood markers and gender, applied in the field of bioinformatics, can solve the problems of high cost and difficulty in obtaining DNA information, and achieve the effects of low cost, low difficulty in use, and high accuracy

Inactive Publication Date: 2021-03-12
天津奇云诺德生物医学有限公司
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Problems solved by technology

[0005] Existing methods for judging or predicting individual gender require the participation of individual entities or the use of DNA information, but DNA information is difficult and expensive to obtain. Therefore, a method for predicting gender using blood markers is designed, which will be more clinically applicable. Universal and more accessible blood markers are used as characteristic values ​​to predict individual gender, which reduces the cost and difficulty of gender determination, and has practical significance and good application prospects

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  • Method of predicting gender by using blood marker
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Embodiment Construction

[0020] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0021] see figure 1 , a method for predicting gender using blood markers, this method is a method for predicting gender of subject samples using common blood markers, the 19 blood markers significantly correlated with gender obtained based on statistical tests are Features, combined with the blood marker data and phenotype data of 92,062 samples collected by the company, using the deep neural network (DNN) algorithm to build a machine learning model, and condu...

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Abstract

The invention relates to the field of biological information, and discloses a method for predicting gender by using a blood marker. The method comprises the following four steps of: collecting blood marker data, preprocessing the data, establishing and evaluating a model and testing the model. Compared with other methods and markers, the selected blood marker, namely a blood biochemical index, isthe most common index in clinical and physical examination institutions, the acquisition difficulty is low, the cost is low, and meanwhile, a machine learning model is used for calculating the selected blood marker, so that the process is more intelligent, and the result is more accurate.

Description

technical field [0001] The invention relates to the field of biological information, in particular to a method for predicting gender by using blood markers. Background technique [0002] Gender refers to the difference between male and female. At the chromosome level, humans have 22 pairs of autosomes and a pair of sex chromosomes. The sex chromosomes of males are XY, and the sex chromosomes of females are XX. The existence of Y chromosomes is also one of the methods for judging human sex; SRY is usually used at the genetic level The testis-determining gene is used as the basis for gender judgment, and the SRY gene is located on the Y chromosome, so individuals with the SRY gene are male, and those without the SRY gene are female; at a more macro level, gonads, genitals, etc. can be used as the basis for gender division . [0003] Studies at home and abroad have shown that some blood indicators are different between male and female individuals, and these different indicato...

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Application Information

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IPC IPC(8): G01N15/00G01N35/00G06N20/00G01N33/50
CPCG01N15/00G01N33/50G01N35/00G06N20/00G01N15/01
Inventor 罗奇斌申玉林廖胜光任毅
Owner 天津奇云诺德生物医学有限公司
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