Code disc structure and microfluidic analysis device for microfluidic positioning

Abstract

This application relates to a code disc structure and a microfluidic analysis device for microfluidic positioning. The code disc structure includes a code disc and a positioning device; the code disc rotates synchronously with the chip mounting disc of the microfluidic analysis device; the code disc is provided with at least Two positioning ports, each positioning port is used to correspond to a measurement chamber of the microfluidic analysis device; the positioning device has an avoidance groove and a positioning place, the code disc part is located in the avoidance groove and there is a gap with the positioning device, and the positioning device is used for Positioning is carried out when each positioning port of the code disc passes through the positioning position. It solves the problem that the measurement cavity cannot be installed and positioned accurately at one time, which leads to the need to identify the position of the microfluidic chip measurement cavity through an algorithm, avoids the disadvantages of pre-stored large amounts of data to identify the measurement cavity, and uses the principle of mechanical positioning with a code disc , Corresponding the code disc outside the temperature zone with the measurement chamber of the microfluidic chip such as the PCR chamber one by one, and adopting the method of identifying the measurement chamber by the code disc to achieve permanent positioning.

Description

technical field [0001] The present application relates to the field of centrifugal microfluidics, in particular to a code disc structure for microfluidic positioning and a microfluidic analysis device. Background technique [0002] Microfluidics system refers to a device that manipulates liquids on the submillimeter scale from a few microns to hundreds of microns. It integrates the basic operating units involved in the fields of biology and chemistry, and even integrates the functions of the entire laboratory, including sampling, dilution, reaction, separation, detection, etc., on a small chip, so it is also called Lab-on-a-Chip (Lab-on-a-Chip). -a-Chip). This kind of chip is generally composed of various liquid storage pools and interconnected microchannel networks, which can greatly shorten the sample processing time, and realize the maximum utilization efficiency of reagent consumables through precise control of liquid flow. Microfluidics provides extremely broad prospe...

AI Technical Summary

Problems solved by technology

[0004] However, a major problem in molecular diagnosis based on centrifugal microfluidics is that the PCR chamber cannot be installed and positioned precisely at one time, especially the position of the PCR chamber on different chips may vary greatly

Therefore, most of them use algorithms to identify the position of the PCR chamber of the chip, which will pre-store a large amount of data to identify the PCR chamber and increase the storage burden of the program software; and each installation will have different errors. After installation, it must be calibrated by software algorithm, increasing repetitive work

Images