System for evaluating risk that suspected sicca syndrome patient receives lip gland biopsy to obtain positive pathological result

A Sjogren's syndrome, positive technology, applied in the medical field, can solve the problems of unpublished lip gland biopsy results of patients, and the absence of assessment methods and systems that can predict the risk of positive pathological results in patients, etc.

Pending Publication Date: 2021-03-30
SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the existing technology has not disclosed a method and system that can predict whether a patient's lip gland biopsy result is positive, and there is no assessment method and system that can predict the risk of a patient receiving a lip gland biopsy to obtain a positive pathological result

Method used

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  • System for evaluating risk that suspected sicca syndrome patient receives lip gland biopsy to obtain positive pathological result
  • System for evaluating risk that suspected sicca syndrome patient receives lip gland biopsy to obtain positive pathological result
  • System for evaluating risk that suspected sicca syndrome patient receives lip gland biopsy to obtain positive pathological result

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Experimental program
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Embodiment 1

[0035] A system for assessing the risk of positive pathological results of labial gland biopsy in patients with suspected Sjogren's syndrome, the system includes an ultrasound score measurement module, a total ultrasound score summary module, a SWE elasticity value measurement module, a total SWE elasticity value summary module, and a comparison judgment module and risk result display module; the ultrasound score measurement module uses B-ultrasound multi-section scanning to scan four glands of the bilateral parotid gland and submandibular gland, and performs a semi-quantitative score of 0 to 4 points for each gland, and obtains the score of each gland. Ultrasonic score, the ultrasound score determination module transmits the ultrasound scores of the four glands to the total ultrasound score summary module, and the total ultrasound score summary module adds the ultrasound scores of the four glands to obtain the total ultrasound score; the SWE elastic value measurement The modul...

Embodiment 2

[0050] A system for evaluating the risk of positive pathological results of labial gland biopsy in patients with suspected Sjogren's syndrome, the system includes an ultrasound score measurement module, a total ultrasound score summary module, a SWE elasticity value measurement module, a total SWE elasticity value summary module, a risk probability Calculation module, comparison judgment module and risk result display module; the ultrasound score measurement module uses B-ultrasound multi-section scanning to scan the four glands of the bilateral parotid gland and submandibular gland, and performs a semi-quantitative score of 0 to 4 points for each gland, Obtain the ultrasound score of each gland, the ultrasound score determination module transmits the ultrasound scores of four glands to the total ultrasound score summary module, and the total ultrasound score summary module adds the ultrasound scores of the four glands to obtain the total ultrasound score; The above-mentioned S...

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Abstract

The invention discloses a system for evaluating the risk that a suspected sicca syndrome patient receives lip gland biopsy to obtain a positive pathological result. The system comprises an ultrasonicscore measuring module, a total ultrasonic score summarizing module, a shear-wave elastography (SWE) elasticity value measuring module, a total SWE elasticity value summarizing module, a comparison and judgment module and a risk result display module. According to the system, through total ultrasonic scores and total SWE elasticity values of four glands including parotid glands and submandibular glands on two sides, it can be evaluated that the risk of a positive pathological result obtained by lip gland biopsy of a suspected sicca syndrome patient is high, medium or low. Besides, a logistic regression equation of interaction is used, the risk probability that the corresponding lip gland biopsy result is positive is calculated according to the total ultrasonic score and the total SWE elasticity value, and a risk probability calculation module is established, so that the risk probability value of the positive pathological result obtained by receiving lip gland biopsy by the suspected sicca syndrome patient is evaluated precisely and quantitatively, a clinician can decide whether to perform clinical decisions such as labial gland biopsy on the patient or not according to the risk judgment result, and a clinical decision mode of guiding invasive biopsy through a non-invasive technology is met.

Description

technical field [0001] The invention belongs to the field of medical technology. More specifically, it relates to a system for assessing the risk of positive pathological results of labial gland biopsy in patients with suspected Sjogren's syndrome. Background technique [0002] Sjogren's syndrome is a chronic inflammatory autoimmune disease mainly involving exocrine glands, also known as autoimmune exocrine gland epithelial cell inflammation or autoimmune exocrine disease. In addition to the decreased function of the salivary glands and lacrimal glands resulting in dry mouth and dry eyes, other exocrine glands and other organs outside the glands are also involved, resulting in multi-system damage symptoms. Sjogren's syndrome is divided into two types: primary and secondary. The prevalence of Sjögren's syndrome in our country is 0.33% to 0.77%, and it is as high as 3% to 4% in the elderly population. There is a uniform "gold standard" of labial gland pathology for each cla...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/20G16H50/30A61B8/08
CPCG16H50/20G16H50/30A61B8/5223
Inventor 莫颖倩戴冽马剑达林建子郝少云
Owner SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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