A concentration and filtration process for preparing pharmaceutical intermediates

Abstract

The invention discloses a concentration and filtration process for preparing pharmaceutical intermediates in the technical field of a concentration and filtration process for pharmaceutical intermediates. The process includes the following steps: Step 1: adding the heated raw liquid of pharmaceutical intermediates to equipment for concentration and filtration ; The present invention uses structures such as fan-shaped bumps, linkage devices and blowing devices, and uses the touch rod to squeeze the fan-shaped bumps to make it move up and down, thereby realizing the vibration of the entire filter device, so that the colloid of the macromolecules Impurities such as cellulose and cellulose are vibrated and dislocated on the surface of the filter membrane, causing the filter gap to leak out. At the same time, when the disc rises, the air bag will be squeezed, and the gas will be blown out through the outlet hole on the outlet pipe, and the blown gas will be on the surface of the filter membrane. Impurities such as colloid and cellulose are blown to scatter them and prevent them from accumulating, increasing the number of filtration voids on the surface of the filter membrane and improving filtration efficiency.

Description

technical field [0001] The invention relates to the technical field of concentration and filtration process for pharmaceutical intermediates, in particular to a concentration and filtration process for preparing pharmaceutical intermediates. Background technique [0002] Pharmaceutical intermediates are some chemical raw materials or chemical products used in the process of pharmaceutical synthesis. This kind of chemical product does not require a drug production license, and can be produced in ordinary chemical factories. As long as it reaches a certain level, it can be used in the synthesis of drugs. [0003] In the prior art, the invention case of the concentration and filtration process of some pharmaceutical intermediates is disclosed. The Chinese patent application number of the invention patent is 201811482089.4, which adopts three-stage filtration to separate traditional Chinese medicine products. For the removal of ineffective or effective components such as macrom...

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Problems solved by technology

[0006] The object of the present invention is to provide a kind of concentration filtration process for preparing pharmaceutical intermediates, to solve the prior art proposed in the above-mentioned background technology in the concentration filtration process of pharmaceutical intermediates, the colloid and fiber of the macromolecule that filter down Impurities such as factors will adhere to the surface of the filter membrane. As the filtration progresses, impurities such as macromolecular colloids and cellulose on the surface of the filter membrane will continue to accumulate and block the gaps on the surface of the filter membrane, so that the filtration efficiency becomes low. There will even be a problem that part of the original solution cannot pass through the filter membrane in the follow-up

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