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Feed additive for improving breeding quantity of queen bees and feed containing feed additive

A feed additive and feed technology, applied in the field of feed additives, can solve the problems of limited acceptance of artificial queen bees, cumbersome operation, and not too many queen bees

Active Publication Date: 2021-05-11
BEE RES INST CHINESE ACAD OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current common method is to induce bees to breed queens by adding artificial queens to the hive, but this operation is cumbersome and cannot be separated from the bee colony. Due to the limited acceptance of artificial queens by bees, the number of queen bees cultivated is not too much

Method used

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  • Feed additive for improving breeding quantity of queen bees and feed containing feed additive
  • Feed additive for improving breeding quantity of queen bees and feed containing feed additive

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Embodiment 1

[0024] In 1974, a methyl group on adenine was first discovered in mRNA. This modified base is called N6-methyladenosine (N6-methyladenosine), abbreviated as m 6 a. The inventor has carried out following experiment:

[0025] 1. m in worker bee larvae 6 A methylation content was significantly higher than that of queen bee larvae

[0026] The honeybees used were Italian honeybees (Apis mellifera), which were purchased from apiaries and raised by beekeepers.

[0027] Five larval samples were collected at three larval developmental stages of queen and worker bees: 1-day-old larvae, 3-day-old queen and worker larvae, and 5-day-old queen and worker bee larvae. The mRNA was isolated from these five samples, and the m 6 A level of methylation. see results figure 1 Figure A shows that no matter the age of 3 days or 5 days, the m 6 The A level was higher than that of queen bee larvae at the same age.

[0028] by m 6 A-seq technology, using m 6 Antibody A (company Synaptic Syste...

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Abstract

The invention provides a feed additive for improving the breeding quantity of queen bees. The active component of the feed additive is 3-denitrified adenosine. Experiments show that the m6A methylation level of the whole larva can be obviously reduced by applying DAA with a certain concentration to worker bee larvae fed with worker bee feed, and the characteristics of the queen bees are induced to develop. Therefore, the queen bees can be bred in batches by only using the worker bee feed with relatively low cost under the condition of artificial culture by applying the DAA, and the method is a quick, efficient and controllable queen bee breeding method.

Description

technical field [0001] The invention specifically relates to a feed additive for increasing the breeding capacity of queen bees and feed containing the feed additive. Background technique [0002] In the process of honeybee hierarchy differentiation, female bee larvae with the same genetic material develop into two distinct hierarchies of fertile queen bee and sterile worker bee due to different food. The number of queen bees is very small. Under natural circumstances, a bee colony only breeds one queen bee. However, in actual production, it is necessary to cultivate a large number of queen bees to expand the number of bee colonies, produce royal jelly or breed queen bee varieties, so as to achieve the purpose of improving the quality and production of bee products. The current general method is to induce bees to breed queens by adding artificial queens in the hive, but this is cumbersome and cannot be separated from the bee colony. Because the acceptance of artificial quee...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K50/90A23K20/121A23K20/137A23K10/20A23K10/16A23K20/163
CPCA23K50/90A23K20/121A23K20/137A23K10/20A23K10/16A23K20/163Y02P60/87
Inventor 王妙吴黎明薛晓锋齐素贞赵柳微王凯王晓颖
Owner BEE RES INST CHINESE ACAD OF AGRI SCI
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