Composition containing animal placenta exosomes as well as preparation method and application of composition

A technology of animal placenta and exosomes, which is applied in the direction of medical preparations containing active ingredients, skin care preparations, pharmaceutical formulas, etc., can solve the problems of limited use, easy breakage, and vesicle rupture, and achieve good results. The effect of protection, storage and transportation cost reduction, and improvement of parcel efficiency

Inactive Publication Date: 2021-05-28
GUANGZHOU SALIAI BIOLOGICAL GENETIC ENG CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Because exosomes exist in the form of vesicles, during the production, storage and transportation of products containing exosomes on the market, exosomes directly contact other components in the product, such as emulsifiers, ions and other substances, cells The vesicles of exosomes are prone to rupture, causing the internal functional components to leak out, be oxidized or denatured, and reduce the efficacy of skin care products
When using skin care products, the vesicle structure of cellular exosomes is very easy to break during the application process. Most cellular exosomes release internal active factors in a short period of time, which will quickly oxidize or denature the functional ingredients, resulting in skin care damage. not lasting
In addition, the products containing exosomes on the market have low transparency, and it is impossible to add a large amount to transparent products, which limits their use

Method used

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  • Composition containing animal placenta exosomes as well as preparation method and application of composition
  • Composition containing animal placenta exosomes as well as preparation method and application of composition
  • Composition containing animal placenta exosomes as well as preparation method and application of composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] The embodiment of the present application provides a composition containing animal placental exosomes, the preparation method of which is as follows:

[0062] According to the ingredients of each composition in Table 2, mix phase A, heat to 80±2°C, stir until completely dissolved, then cool down to 40±2°C; mix phase B evenly, add to the cooled phase A, stir Uniformly, Composition 2 was obtained.

[0063] The light transmittance of the composition 2 was 78.79% as detected by the ultraviolet spectrophotometer.

[0064] Table 2

[0065]

Embodiment 2

[0073] The embodiment of the present application provides a composition containing animal placenta exosomes, the preparation method of which is as follows:

[0074] According to the ingredients of each composition in Table 4, mix phase A, heat to 80±2°C, stir until completely dissolved, then cool down to 40±2°C; mix phase B evenly, add to the cooled phase A, stir Uniformly, composition 4 was obtained.

[0075] The light transmittance of the composition 4 was 85.16% as detected by the ultraviolet spectrophotometer.

[0076] Table 4

[0077]

Embodiment 3

[0079] The embodiment of the present application provides a composition containing animal placenta exosomes, the preparation method of which is as follows:

[0080] According to the ingredients of each composition in Table 5, mix phase A, heat to 80±2°C, stir until completely dissolved, then cool down to 40±2°C; mix phase B evenly, add to the cooled phase A, stir Uniformly, Composition 5 was obtained.

[0081] The light transmittance of the composition 5 was 82.73% as detected by the ultraviolet spectrophotometer.

[0082] table 5

[0083]

[0084]

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Abstract

The invention belongs to the technical field of biology, and particularly relates to a composition containing animal placenta exosomes as well as a preparation method and application of the composition. The composition containing animal placenta exosomes comprises the following components in percentage by mass: 0.05-5% of animal placenta exosome freeze-dried powder, 1-20% of a humectant, 0.05%-5% of a micro-capsule wrapping material, 0.01-2% of a vitamin E derivative, and the balance of water, wherein the microcapsule wrappage is selected from one or more of soybean lecithin, hydrogenated soybean phospholipid, hydroxylated lecithin, cyclodextrin and hydroxypropyl cyclodextrin. The invention provides a composition containing animal placenta exosomes as well as a preparation method and application of the composition, and a complete animal placenta exosome vesicle structure is reserved in a storage and transportation process; and the content of the animal placenta exosomes is slowly released in the use process, so that the effect of the animal placenta exosomes is realized.

Description

technical field [0001] The application belongs to the field of biotechnology, and in particular relates to a composition containing animal placental exosomes and a preparation method and application thereof. Background technique [0002] The skin is the largest organ on the surface of the human body. It is in direct contact with the external environment and resists external oxidation, drying, ultraviolet rays and other factors. And because of the influence of internal factors such as age, diet, living habits and work pressure, free radicals in skin cells increase, collagen is lost, resulting in skin dehydration and nutritional deficiencies, resulting in skin aging and wrinkles. For a long time, in the face of skin aging and wrinkles, people have used various methods to cover up and treat them. [0003] Relevant research in modern biology and medicine has found that cellular exosomes can be used externally on the human body, can be absorbed through the skin, and can introduc...

Claims

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Application Information

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IPC IPC(8): A61K8/99A61K8/67A61K8/86A61K8/55A61K8/73A61K8/44A61K8/88A61Q19/08A61Q19/00
CPCA61K8/99A61K8/678A61K8/86A61K8/553A61K8/738A61K8/44A61K8/88A61Q19/08A61Q19/00A61Q19/005A61K2800/622A61K2800/624A61K2800/84A61K2800/65
Inventor 陈海佳李保耀庞可亮李学家陈东煌姜交华严心铭
Owner GUANGZHOU SALIAI BIOLOGICAL GENETIC ENG CO LTD
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