Tangshen Qushi Prescription and Its Application

A technology for diabetic nephropathy and spleen and kidney qi deficiency, which can be applied to medical formulas, medical preparations containing active ingredients, allergic diseases, etc., and can solve problems such as unsatisfactory treatment effects

Active Publication Date: 2022-05-10
GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Affected by geographical environment factors, the Lingnan area is hot and humid, and a considerable number of diabetic nephropathy patients belong to the type of damp syndrome, blood stasis, spleen and kidney qi deficiency, and spleen and kidney yang deficiency, but the traditional Chinese medicine in the prior art is not ideal for the treatment of such patients

Method used

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  • Tangshen Qushi Prescription and Its Application
  • Tangshen Qushi Prescription and Its Application
  • Tangshen Qushi Prescription and Its Application

Examples

Experimental program
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Effect test

Embodiment 1

[0030] The Tangshen Qushi traditional Chinese medicine decoction of this embodiment consists of the following raw materials in parts by mass: 20 g of astragalus, 15 g of Cuscuta salt, 10 g of peach kernel, 10 g of atractylodes rhizome, 10 g of tangerine peel, 15 g of centella asiatica, and 10 g of cicadae.

[0031] Its preparation method comprises the following steps:

[0032] Weigh the crude drug according to the proportion, add 10 times the weight of water, heat to boil and keep boiling for 1h, filter to obtain the first filter residue and the first filtrate, then add water 8 times the weight of the first filter residue, heat to boil and keep Slightly boil for 1h, filter to obtain the second filter residue and the second filtrate, and combine the first filtrate and the second filtrate to obtain the obtained product.

[0033] The traditional Chinese medicine decoction that present embodiment makes is one dosage, and one dosage is 200mL.

[0034] In addition, in order to obta...

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Abstract

The invention belongs to the field of traditional Chinese medicine, and in particular relates to a Tangshen Qushi prescription and its application. The main active ingredients include: 9-30 parts of astragalus, 6-15 parts of dodder seed, 5-10 parts of peach kernel, and 3-30 parts of atractylodes rhizome in parts by weight. 10 parts, 3-10 parts of tangerine peel, 15-30 parts of centella asiatica, 3-10 parts of cicadae. The invention also provides the application of Tangshen Qushi formula. Clinical trials have shown that the Tangshen Qushi prescription of the present invention can significantly increase the glomerular filtration rate eGFR and significantly decrease the serum creatinine Cr in patients with diabetic nephropathy, and is mild to urine protein (1202.15 ± 784.85), CKD more than 3 stages (eGFR 25-75mL / min / 1.73m 2 ) patients have clear renal function protection.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a Tangshen Qushi prescription and its application. Background technique [0002] Diabetic kidney disease (DKD) is one of the most important microvascular complications of diabetes (diabetes mellitus, DM), which not only leads to the occurrence of end-stage renal disease, but also increases the incidence of cardiovascular-related events in patients. One of the leading causes of death in diabetic patients. In my country, DKD is the second leading cause of end-stage renal disease (ESRD) after chronic glomerular disease, and there is an upward trend in recent years. [0003] For the treatment of diabetic nephropathy, Western medicine mainly focuses on lowering blood pressure, lowering blood sugar, and reducing proteinuria. Currently, the recommended drugs mainly include angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor blocker (ARB). ,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61K9/00A61K9/08A61P3/10A61P9/14A61P13/12A61P37/02A61K35/64
CPCA61K36/481A61K36/39A61K36/43A61K36/736A61K36/284A61K36/752A61K36/23A61K36/068A61K35/64A61K9/0095A61P3/10A61P9/14A61P13/12A61P37/02A61K2300/00
Inventor 刘旭生张蕾卢富华陈国伟许苑张腊苏镜旭胡晓璇郑婷婷吴一帆揭西娜刘惠谢小宁傅立哲
Owner GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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