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Diagnosis and treatment system for precancerous lesions of gastrointestinal tract

A technology of precancerous lesions, diagnosis and treatment system, applied in the directions of diagnosis, gastroscope, esophagoscopy, etc., can solve problems such as battery capacity limitation, inability to diagnose precancerous lesions, and lack of treatment functions, and achieve the effect of improving accuracy

Pending Publication Date: 2021-09-03
SHANGHAI JIAO TONG UNIV +1
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing capsule endoscope can only relieve the pain of the examinee, but it cannot solve another major problem of the current conventional insertion endoscope, that is, the inspection can only be based on the change of the surface morphology of the gastrointestinal tract. It is impossible to diagnose precancerous lesions that do not cause obvious changes in the surface of the gastrointestinal tract. At the same time, it is difficult to find precancerous lesions in the folds and collapses of the gastrointestinal tract, and it cannot cooperate with biopsy, which may easily lead to missed or misdiagnosed
And limited by the battery capacity, it is not possible to conduct a long-term diagnosis of the entire digestive tract
At the same time, the existing commercial capsule endoscopes do not have therapeutic functions.
[0006] Therefore, there is still no ideal system for early screening of gastrointestinal precancerous lesions

Method used

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  • Diagnosis and treatment system for precancerous lesions of gastrointestinal tract
  • Diagnosis and treatment system for precancerous lesions of gastrointestinal tract
  • Diagnosis and treatment system for precancerous lesions of gastrointestinal tract

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Embodiment Construction

[0034] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, but not to limit the present invention.

[0035] refer to figure 1 - image 3 As shown, the present invention provides a system for diagnosing and treating precancerous lesions of the gastrointestinal tract, which includes a capsule endoscope 2 and a targeted probe that can specifically identify precancerous lesions of the gastrointestinal tract used in conjunction with the capsule endoscope 2. The needle 1; the capsule endoscope 2 is a capsule endoscope 2 with light sources of three wavelengths, a position control module 204 inside the capsule endoscope 2, and an external image receiving module 3 .

[0036] In this embodiment, the ...

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Abstract

The invention provides a diagnosis and treatment system for precancerous lesions of gastrointestinal tract. The diagnosis and treatment system comprises a targeting probe capable of specifically recognizing precancerous lesions of the gastrointestinal tract, and one or any combination of antibodies in antibodies corresponding to proteins corresponding to gene banks with GenBank acceptance numbers of AF054162, AF054163, AF054164 and the like which can be adsorbed to the precancerous lesions of the gastrointestinal tract in a targeting manner and are highly expressed in precancerous lesion tissue. At least one or any combination of a molecular contrast agent and a light-absorbing and heat-producing functional substance is coupled to the antibodies. The capsule endoscope at least comprises a white light module, an ultraviolet light module and a near-infrared light module and is provided with multiple wavelength light sources, a capsule endoscope in-vivo position control module and an in-vitro image receiving module, the probe can specifically recognize and be adsorbed to the precancerous lesions of the gastrointestinal tract, targeted imaging detection is achieved under irradiation of the specific light source of the capsule endoscope, and the detection accuracy is improved. A novel specific detection and treatment system is provided for gastrointestinal precancerous lesions.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to a system for diagnosing and treating precancerous lesions of the gastrointestinal tract. Background technique [0002] Gastrointestinal cancer has extremely high morbidity and mortality, and is one of the major diseases threatening human health. Gastrointestinal cancers are all evolved from precancerous lesions of the gastrointestinal tract, including gastric ulcers, gastric polyps, chronic atrophic gastritis, intestinal gland metaplasia, and dysplasia. At present, the early detection rate of gastrointestinal precancerous lesions in my country is low, and most of them are not treated in time, which increases the probability of evolving into cancer and directly causes the extremely high incidence of gastrointestinal cancer. The low detection rate of gastrointestinal precancerous lesions can be partly attributed to the fact that the symptoms are not obvious in the early stage, and a...

Claims

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Application Information

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IPC IPC(8): A61B1/00A61B1/04A61B1/045A61B1/06A61B1/273A61B1/31A61B5/00A61B18/04
CPCA61B1/041A61B1/043A61B1/00009A61B1/00016A61B1/2736A61B1/31A61B5/0084A61B5/0086A61B1/0661A61B1/0638A61B18/04A61B1/045A61B1/00158A61B2018/00494
Inventor 崔大祥周诚史楠清沈琦彭家伟梁辉
Owner SHANGHAI JIAO TONG UNIV
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