Alcohol use disorder clinical poor prognosis prediction model and construction method thereof

A technology for poor prognosis and prediction model, applied in the medical field, can solve the problem of lack of index system of clinical prognosis of alcohol use disorder and so on

Pending Publication Date: 2021-09-10
昆明医科大学第二附属医院
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Problems solved by technology

However, there has been no in-depth research to explore specific clinical prognosis assessment methods, and there is even a lack of corresponding index system to systematically evaluate the clinical prognosis of alcohol use disorder

Method used

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  • Alcohol use disorder clinical poor prognosis prediction model and construction method thereof
  • Alcohol use disorder clinical poor prognosis prediction model and construction method thereof
  • Alcohol use disorder clinical poor prognosis prediction model and construction method thereof

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Experimental program
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Embodiment 1

[0016] A method for constructing a poor clinical prognosis prediction model for alcohol use disorder, comprising the following steps:

[0017] (1) 148 patients with alcohol use disorder and 96 normal controls were enrolled, and the data of individual factors were collected, including gender, age, education level, daily alcohol consumption, and drinking time limit. Table) score, PHQ-9 (Patient Health Questionnaire) score, GAD-7 (Generalized Anxiety Scale) score, and PSQI (Pittsburgh Sleep Quality Index Scale) score were used as alcohol use severity, depression, anxiety, sleep For the psychological factor data of symptoms, the subject's DSST (number symbol substitution test) score, the latency and amplitude data of the event-related potential P300 at Fz, Cz and Pz points are used as the cognitive function factor data.

[0018] 148 patients with alcohol use disorder were given drug treatment for 8 weeks, and the patients were divided into two groups according to the AUDIT score r...

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Abstract

The invention discloses an alcohol use disorder clinical poor prognosis prediction model and a construction method thereof According to the method, an alcohol use disorder clinical poor prognosis prediction model is established mainly according to psychological evaluation indexes and prediction values of electrophysiological markers. The alcohol use disorder clinical poor prognosis prediction model constructed by the invention can achieve the clinical target of early screening of patients with poor prognosis, is used for judging the clinical prognosis of alcohol use disorder, makes early prognosis prediction, early timely intervention and prognosis improvement possible, and has important clinical significance.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a predictive model of poor clinical prognosis of alcohol use disorder and a construction method thereof. Background technique [0002] Alcohol use disorder is one of the most serious mental disorders and a serious public health problem. According to the epidemiological survey in 2019, the lifetime prevalence rate of alcohol use disorder in my country is 4.4%, which has become the most common substance abuse in my country. [0003] At present, there are not many treatment methods for alcohol use disorder, and the treatment effect is not good. There is even a lack of corresponding methods and standards for the evaluation of its clinical prognosis, which also affects the objective evaluation of the clinical treatment effect of the disease. [0004] In clinical research, it has been found that in addition to the abnormal behavior of alcohol use, patients with this disea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/70G16H20/70
CPCG16H50/70G16H20/70
Inventor 杨建中彭英元静王新孟骏宇曾婷婷曾晓舟冯祖幸金于雄范昕昕王鸿轩
Owner 昆明医科大学第二附属医院
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