Bacteriostatic and/or desensitizing oral paste

Abstract

The invention belongs to the technical field of pharmaceutical preparations, in particular to an antibacterial and / or desensitizing oral paste. The oral paste disclosed by the invention comprises desensitizing active ingredients, antibacterial active ingredients, binder, solid matrix, antioxidant and solvent. By optimizing the type and proportion of desensitizing active ingredients, optimizing the ratio of desensitizing active ingredients and antibacterial active ingredients, and the types and amounts of other excipients, the desensitization and antibacterial effects of this product are jointly improved. The type and dosage solve the problem that the active ingredients are easily oxidized and improve the stability of the product.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, in particular to a bacteriostatic and / or desensitizing oral paste. Background technique [0002] Dentin hypersensitivity is defined as transient pain arising from exposed dentin, usually in response to chemical, thermal, tactile or osmotic stimuli, which cannot be explained by any other dental defect or pathology. Erosion of the outer surface of the tooth (enamel) and / or gingival recession often results in exposure of dentinal tubules, creating pathways between nerve fibers in the oral cavity and the pulp. In vivo, it has been shown that there is a pressure gradient across the dentin, which causes the fluid to flow outward. This fluid flow is disturbed or increased in response to touch, temperature (hot or cold), and osmotic stimuli (high concentrations of sugar, etc.), which are thought to result in mechano-stimulatory receptor responses (detected as pain) of nerve fibers wi...

AI Technical Summary

Problems solved by technology

[0005] Overcoming the deficiencies of the prior art, the present invention solves the problem that the active ingredient is easily oxidized by optimizing the screening of main and auxiliary materials and improving the formulation of the preparation, and provides a long-term stability that can effectively relieve tooth sensitivity and / or oral cavity depression. oral paste

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