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Application of polypeptide in regulating and controlling in-vitro culture of fibroblasts

A fibroblast and in vitro culture technology, which is applied in the field of peptide regulation in the in vitro culture of fibroblasts, and can solve problems such as high price, damage to skin health, and safety issues

Active Publication Date: 2021-11-09
渤海水产股份有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many kinds of products used for skin care or makeup, but most of them rely on the nature of the chemical ingredients in skin care products or cosmetics, which have many side effects and even damage skin health, causing safety problems
Safe and effective skin care products or cosmetics aimed at activating the skin's own physiological functions are often expensive and cannot be popularized and applied. Therefore, it is urgent to develop a safe and effective skin care or cosmetic product that can activate the skin's own physiological functions.

Method used

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  • Application of polypeptide in regulating and controlling in-vitro culture of fibroblasts
  • Application of polypeptide in regulating and controlling in-vitro culture of fibroblasts
  • Application of polypeptide in regulating and controlling in-vitro culture of fibroblasts

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] This group of embodiments provides a polypeptide composed of the amino acid sequence shown in SEQ ID No.1.

Embodiment 2

[0046] This embodiment provides a skin toner, the specific composition of which is shown in Table 1.

[0047] Toner component list in Table 1 Example 2

[0048]

Embodiment 3

[0050] This embodiment provides a skin toner, the specific composition of which is shown in Table 2.

[0051] Table 2 Table of toner components in Example 3

[0052]

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PUM

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Abstract

The invention relates to the technical field of cosmetics, and particularly relates to application of polypeptide in regulating and controlling in-vitro culture of fibroblasts. The invention discovers for the first time that the polypeptide composed of an amino acid sequence shown in SEQ ID No. 1 can promote in-vitro proliferation of fibroblasts and collagen secretion, the promotion effect is remarkable and stable, that the polypeptide has a remarkable effect of delaying skin aging is determined, the polypeptide is expected to be used as a main component to further develop a product for promoting fibroblast growth, and the product has a good market prospect when used for skin care or cosmetics.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to the application of polypeptides in regulating fibroblast culture in vitro. Background technique [0002] With the improvement of the quality of life, people pay more and more attention to the problem of skin aging. With age, the skin will undergo degenerative changes, and its function will gradually weaken or lose, manifested in the decrease of skin cell proliferation, the slowing of epidermal renewal, the weakening of epidermal reconstruction, and the slowing down of dermal collagen synthesis. Therefore, Research on bioactive substances that can proliferate and repair at the cellular level and fundamentally delay skin aging is of great significance and value to the development of the medical and cosmetic industries. [0003] At present, there are many kinds of products used for skin care or makeup, but most of them rely on the nature of the chemical ingredients in skin care p...

Claims

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Application Information

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IPC IPC(8): C12N5/077A61K8/64A61Q19/00A61Q19/08
CPCA61K8/64A61Q19/00A61Q19/08C12N5/0656C12N2501/999
Inventor 宋淑亮陈锚潘炳旗王珂杨琼关浩马士玉张新峰
Owner 渤海水产股份有限公司