Traditional Chinese medicine composition for treating lung cancer and preparation method and application thereof

The technology of a composition and a pharmaceutical preparation is applied in the field of traditional Chinese medicine compositions for the treatment of lung cancer and the preparation thereof, which can solve the problems of toxic and side effects, multidrug resistance, poor treatment effect, etc. effects of immune regulation

Pending Publication Date: 2021-11-12
SHANDONG UNIV
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional therapies such as chemotherapy and radiotherapy are the main means of treating lung cancer. There are multidrug resistance and serious side effects, and the treatment effect is not good.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition for treating lung cancer and preparation method and application thereof
  • Traditional Chinese medicine composition for treating lung cancer and preparation method and application thereof
  • Traditional Chinese medicine composition for treating lung cancer and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0060] In another specific embodiment of the present invention, the preparation method of the above-mentioned Chinese medicine composition is provided, and the method includes the following steps:

[0061] Grinding the above-mentioned raw medicinal materials, adding ethanol, heating to reflux for extraction, and concentrating to obtain an alcohol extract; adding water to the medicinal residue after alcohol extraction, heating and refluxing for extraction, and concentrating to obtain a water extract, combining the alcohol extract and the water extract , concentrated ointment.

[0062] Wherein, the mass ratio of the raw material drug to ethanol is 1:6-10, such as 1:8; the concentration of ethanol is controlled at 60-100%, such as 70%, 90%, 100%;

[0063] More specifically, during the alcohol extraction process, the specific method of heating to reflux extraction includes: heating to reflux extraction twice, each time for 1 hour, filtering to obtain a filtrate, combining the two ...

Embodiment 1

[0082] Example 1: According to the formula and preparation method disclosed in the present invention, the inventor obtained the Chinese medicinal material extract of Example 1 through the following process: four medicinal materials such as Ganoderma lucidum, Salvia miltiorrhiza, Baibu, and Aodicha were pulverized into coarse powder, Weigh 600 grams of Ganoderma lucidum, 1,000 grams of Salvia miltiorrhiza, 300 grams of Baibu, and 1,500 grams of Aodi tea, add 8 times the amount of 70% ethanol, heat and reflux to extract twice, each time for 1 hour, filter to obtain the filtrate, and combine the two filtrates , use a rotary evaporator to concentrate under reduced pressure to an appropriate amount; add 6 times the amount of deionized water to the dregs after alcohol extraction, heat and reflux extraction twice, each time for 1 hour, filter to obtain the filtrate, combine the two filtrates, and use a rotary evaporator Concentrate under reduced pressure to an appropriate amount; then...

Embodiment 2

[0083]Example 2: According to the formula and preparation method disclosed in the present invention, the inventor obtained the Chinese medicinal material extract of Example 2 through the following process: four medicinal materials such as Ganoderma lucidum, Salvia miltiorrhiza, Baibu, and Aodicha were pulverized into coarse powder, Weigh 1200 grams of Ganoderma lucidum, 1500 grams of Salvia miltiorrhiza, 750 grams of Baibu, and 1000 grams of Aodicha, add 8 times the amount of 90% ethanol, heat and reflux to extract twice, each time for 1 hour, filter to obtain the filtrate, and combine the two filtrates , use a rotary evaporator to concentrate under reduced pressure to an appropriate amount; add 6 times the amount of deionized water to the dregs after alcohol extraction, heat and reflux extraction twice, each time for 1 hour, filter to obtain the filtrate, combine the two filtrates, and use a rotary evaporator Concentrate under reduced pressure to an appropriate amount; then co...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a traditional Chinese medicine composition for treating lung cancer and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from, by weight, 6-24 parts of lucid ganoderma, 10-30 parts of radix salviae miltiorrhizae, 3-18 parts of radix stemonae and 10-60 parts of Japanese ardisia herb. In-vitro and in-vivo curative effect research proves that the traditional Chinese medicine composition and a traditional Chinese medicine preparation thereof have the good effects of regulating immunity, inhibiting tumor cells, resisting metastasis and drug resistance and the like on treating lung cancer, and the safety to subjects is high; meanwhile, the preparation process is optimized, the traditional Chinese medicine composition is prepared through a scientific formula and water-soluble and fat-soluble effective component extraction, and therefore the good practical application value is achieved.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating lung cancer, a preparation method and application thereof. Background technique [0002] The information disclosed in this background section is only intended to increase the understanding of the general background of the present invention, and is not necessarily taken as an acknowledgment or any form of suggestion that the information constitutes the prior art already known to those skilled in the art. [0003] Lung cancer is currently the malignant tumor with the highest morbidity and mortality. It has the characteristics of high metastasis, easy drug resistance, and easy recurrence, which seriously threatens human health and quality of life. In recent years, although great progress has been made in targeted therapy and immunotherapy for lung cancer, the 5-year survival rate is only about 2...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61P35/00A61P35/04A61P37/02
CPCA61K36/074A61K36/537A61K36/904A61K36/185A61P35/00A61P35/04A61P37/02A61K2236/333A61K2236/51A61K2236/331A61K2236/39A61K2300/00
Inventor 李楠赵忠熙齐秋晨
Owner SHANDONG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap