Dormant blood vessel activation method based on low-energy shock waves

Abstract

The invention relates to the technical field of low-energy shock wave treatment, and discloses a dormant blood vessel activation method based on low-energy shock waves. Acute myocardial infarction is treated through the low-energy shock waves, the expression level of local vascular endothelial growth factor mRNA of infarcted myocardium is increased, the number of vascular endothelial cells and the capillary density are obviously increased, development of collateral circulation is promoted, which suggests that the ESW can effectively induce angiogenesis in an ischemic area, reconstruct local myocardial microcirculation and improve ventricular remodeling after myocardial infarction, besides, the level of nitric oxide in plasma is obviously increased after treatment by the low-energy shock waves, fibroblast growth factors and insulin-like growth factors are obviously increased, and a transforming growth factor p1, a soluble intercellular adhesion factor and a soluble vascular cell adhesion factor 1 are all reduced by 121, so that local treatment of the low-energy shock waves can obviously increase the NO level of plasma, an anti-inflammatory effect is achieved, metabolism of a lesion area is improved, and microangiogenesis is promoted.

Description

technical field [0001] The invention relates to the technical field of low-energy shock wave therapy, in particular to a method for activating dormant blood vessels based on low-energy shock waves. Background technique [0002] In recent years, the incidence of ischemic heart disease has gradually increased, and its treatment has also made great progress. At present, drug therapy and percutaneous coronary intervention are the three main methods of clinical treatment, but for some patients who do not have the above treatment indications For patients with ischemic heart disease, the prognosis of various current treatments is relatively poor. On the one hand, the symptoms of angina pectoris are difficult to control, and on the other hand, the heart function is low and the heart is enlarged due to myocardial ischemia. Extracorporeal shock wave is a non-invasive treatment technology superior to other minimally invasive treatments. It is a safe, economical, Reliable treatment met...

AI Technical Summary

Problems solved by technology

[0004] Aiming at the deficiencies of the prior art, the present invention provides a method for activating dormant blood vessels based on low-energy shock waves, which solves the problem