The invention discloses a compound feed capable of increasing the effective litter size of sows. The compound feed is prepared from the following raw materials in parts by weight: corn, soybean meal, bran, wheat middling, soybean oil, fat powder, soybean fibers, edible salt, choline, limestone powder, calcium hydrogen phosphate, an acidifier, a mildew preventive, lysine, glutamine, rice hull powder, phytase, an enzymic preparation, a mold removal agent, an antioxidant, organic chromium, saccharomycetes, a living bacteria agent, VE, biotin, folic acid, ferrous methionine chelate, vitamin A, beta-carotene, VB2, selenium yeast, zinc yeast, N-carbamylglutamic acid, various trace mineral elements and various trace vitamins. After the compound feed is eaten by pregnant sows, the numbers of mummies, dead fetuses and scrawny piglets in the litter size are effectively reduced, and the effective live litter can be increased by 1 per litter.