57 results about "Carbamylglutamic acid" patented technology

The invention relates to a feed, a preparation method and use thereof in improvement in the reproductive performance of sows. The feed is characterized by comprising the following components in percentage by weight: 0.05 to 0.2 percent of N-carbamylglutamic acid and the balance of auxiliary materials. The preparation method comprises the following steps of: 1) removing impurities from the auxiliary materials in percentage by weight, air-drying the auxiliary materials and crushing the auxiliary materials to 20 to 100 meshes; and 2) mixing under stirring the crushed auxiliary materials obtainedin the step 1) and the N-carbamylglutamic acid in percentage by weight, and sieving the mixture to obtain the finished product feed. The feed can enhance the reproductive performance of the sows, canpromote the synthesis of endogenous arginine in the sows and effectively improve the reproductive performance of the sows to further improve the growth performance of piglets.

The invention relates to a method for preparing N-carbamylglutamic acid and application thereof. The method comprises the following steps: (1) according to molar ratio of 0.8-1.6:0.8-1.6:1.6-3.2, glutamic acid, ammonium formate and sodium hydroxide are weighed for standby; (2) the weighed glutamic acid and sodium hydroxide are dissolved in distilled water and are stirred; the obtained mixture is added with the weighed ammonium formate and is stirred; the total mixture reflows for 30 to 55 minutes at a temperature of between 98 and 110 DEG C; and (3) the reaction mixture obtained in the step (2) is cooled to room temperature, is washed by formaldehyde, is filtered, is added with concentrated hydrochloric acid, is acidified, is kept stand at a temperature of between 4 DEG C below zero and 2 DEG C, is crystallized and is filtered to obtain the N-carbamylglutamic acid. Compared with the prior method, the method for preparing the N-carbamylglutamic acid has the following advantages: the method reduces the cost and toxicity of the raw materials, has simple and high-efficient process and is favorable for large-scale production. The N-carbamylglutamic acid prepared through the method has the application that the N-carbamylglutamic can be used as a pig feed additive.

The invention discloses a compound feed capable of increasing the effective litter size of sows. The compound feed is prepared from the following raw materials in parts by weight: corn, soybean meal, bran, wheat middling, soybean oil, fat powder, soybean fibers, edible salt, choline, limestone powder, calcium hydrogen phosphate, an acidifier, a mildew preventive, lysine, glutamine, rice hull powder, phytase, an enzymic preparation, a mold removal agent, an antioxidant, organic chromium, saccharomycetes, a living bacteria agent, VE, biotin, folic acid, ferrous methionine chelate, vitamin A, beta-carotene, VB2, selenium yeast, zinc yeast, N-carbamylglutamic acid, various trace mineral elements and various trace vitamins. After the compound feed is eaten by pregnant sows, the numbers of mummies, dead fetuses and scrawny piglets in the litter size are effectively reduced, and the effective live litter can be increased by 1 per litter.

The invention discloses an application of N-carbamylglutamic acid contained fodder in promoting the growth of pigs, the steps are as follows: a. N-carbamylglutamic acid is pulverized and is sieved by 40 to 100 meshes; b. the N-carbamylglutamic acid powder obtained from step a is fully mixed with premix or complete feed; c. all the components obtained from the step b are added into a blender for being stirred for 6 to 15 minutes according to the proportion, and then the above components are made into granular (or powdery) form and are packaged into bags. The obtained N-carbamylglutamic acid contained fodder is used for feeding suckling piglets, weaning piglets or reserved sows and growing pigs. The N-carbamylglutamic acid contained fodder can promote the protein of the piglets to be synthesized, relieve the weaning stress of the piglets and improve the born number of the sow, therefore, the N-carbamylglutamic acid contained fodder has good application prospect.

The invention discloses a preparation method and application of feed additive N-carbamylglutamic acid. The steps of the preparation method are that: a. L-glutamic acid, methanol and sulfuric acid are mixed and react with each other, and triethylamine is used to regulate the pH value of the mixed solution to obtain L-alpha-methyl glutamate; the obtained L-alpha-methyl glutamate is added into the mixed solution of methanol and carbon disulfide, ammonia is fed in till the mixed solution is saturated, the obtained solution is placed under closed condition, and alpha-methyl ester-L-glutamic acid-N-amino-acid salt concentrated solution is obtained after concentration and ammonia removal; the concentrated solution is heated, acetic acid is added, the pressure is reduced to remove carbon disulfide to obtain crude N-carbamylglutamic acid, the crude N-carbamylglutamic acid is decolorized by active carbon and is recrystallized to obtain the finished product; and b. the N-carbamylglutamic acid is crushed and passes through a sieve, the obtained product is mixed with premix, and the obtained product is put and agitated in an agitator and is prepared into particles. The feed additive N-carbamylglutamic acid can promote the synthesis of endogenous arginine in bodies of piglets and sows. The method is simple, the operation is simple and convenient, the raw materials can be obtained easily and the cost is low. The produced feed can promote the synthesis of piglet proteins, relieve weanling stress of the piglets and improve the productivity of the sows.

The invention discloses boar complete formula feed for improving semen quality. The boar complete formula feed for improving semen quality is prepared from the following raw materials in parts by weight: 60-65 parts of corn, 10-16 parts of bean pulp, 3-8 parts of soybean hull, 5-8 parts of wheat bran, 0.5-1 part of nucleotide, 1-3 parts of imported fishmeal, 0.8-1.1 parts of calcium hydrophosphate, 0.6-0.9 part of mountain flour, 0.1-0.3 part of lysine, 0.1-0.05 part of threonine, 0.2-0.4 part of baking soda, 0.01-0.05 part of selenium yeast, 0.2-0.4 part of salt, 0.1-0.15 part of choline chloride, 0.1-0.5 part of N-carbamylglutamic acid and 1-4 parts of boar premix. The complete formula feed disclosed by the invention has the advantages of improving the ejaculatory amount, sperm motility and sperm density of boars and enhancing the heat-stress resistance of the boars.

The invention discloses a mixed feed for improving antioxidant activity of the sperm of a boar. The mixed feed is characterized by comprising the following raw materials by weight: 40 to 60% of corn, 5 to 20% of fish meal, 5 to 20% of wheat, 10 to 25% of wheat bran, 0.2 to 5% of a soybean small peptide additive, 0.05 to 2% of taurine, 2 to 10% of soybean meal, 2 to 8% of plant oil, 1 to 2% of a calcium element additive, 0.1 to 0.8% of salt, 0.05 to 0.5% of N-carbamylglutamic acid, 0.1 to 0.3% of a composite trace element additive, 0.03 to 0.08% of a composite vitamin additive, 0.005 to 1% of anthocyanidin, 0.05 to 2% of tea polyphenol, 0.5 to 1.5% of amino acid and 0 to 5% of bentonite. The mixed feed is applicable to the boar, can effectively increase the amount of boar seminal fluid, improve sperm vitality and sperm density, reduce the rate of sperm deformation and enhance antioxidant activity of the sperm of the boar and is of great significance to improvement of the quality of boar seminal fluid.

The invention discloses fodder for improving nitrogen utilization rate and production performance of diary cows. The fodder is composed of basic materials and an auxiliary material, wherein the basic materials comprise the following components in parts by weight: 24.2 to 25 parts of silage corn, 13.0 to 15 parts of alfalfa, 5.4 to 6.0 parts of leymus chinensis, 2.0 to 4.0 parts of cottonseed cake, 3.6 to 4.0 parts of bagasse, 15.0 to 15.2 parts of corn, 2.0 to 2.4 parts of wheat bran, 5.07 to 5.47 parts of barley, 2.00 to 2.60 parts of soybean meal, 7.4 to 8.0 parts of bean cake, 5.0 to 5.6 parts of cottonseed meal, 3.00 to 3.08 parts of distillers' grains, 0.71 to 0.91 part of soybean curb residue, 3.0 to 4.0 parts of rapeseed meal, 0.02 to 0.06 part of methionine, 0.31 to 0.71 part of premix, 0.31 to 0.71 part of salt and 0.40 to 0.80 part of calcium bicarbonate; the auxiliary material comprises the component of 0.67 to 1.07 parts of N-carbamylglutamic acid.

The invention discloses a method for continuously synthesizing N-carbamylglutamic acid by using a micro-channel reactor. The method comprises the following steps: (1) preparing a sodium glutamate solution and a urea solution, wherein the concentration of the sodium glutamate solution is 200-700g/L, and the concentration of the urea solution is 300-1000g/L; (2) respectively pumping the sodium glutamate solution and the urea solution into the micro-channel reactor at a volume flow ratio of 1 to (0.2-2.0), passing through a reactor I and a reactor II which are connected in series inside the micro-channel reactor, wherein the total retaining time inside the reactor I and the reactor II is 10-95 minutes, the temperature of the reactor I is 100-150 DEG C, and the temperature of the reactor II is 100-150 DEG C; (3) salting out and refining a material discharged from the micro-channel reactor, so as to obtain a finished product, namely, the N-carbamylglutamic acid. The method is rapid in reaction, high in mixing efficiency, high in conversion rate, less in amount of byproducts, low in cost and applicable to industrial production and application.

The invention relates to a feed containing N-carbamylglutamic acid and N-carbamylglutamic acid sodium salt for boars, preparation and application thereof. The feed is characterized by being prepared from the following components in percentage by weight: 0.10 to 0.25 percent of mixture of the N-carbamylglutamic acid and the N-carbamylglutamic acid sodium salt and auxiliary materials. The feed can promote the synthesis of source arginine in the bodies of boars, enhance the synthesis of carbon monoxide (NO) and polyamine, ensure that the boars exert the genetic potential more effectively, improve the utilization age limit and the health level of the boars and improve the economic benefit of raising the boars.

The invention discloses a synthesis and post-treatment method of high-purity N-carbamylglutamic acid and belongs to the field of organic chemistry and fine chemical engineering. According to the method, sodium glutamate and sodium cyanate are adopted as raw materials to prepare N-carbamoyl sodium glutamate, acidification is performed with sulfuric acid after reaction is completed, then heating is performed to 40-50 DEG C, and filtration is performed to obtain a high-purity product after even stirring; a mother solution is cooled to 0-5 DEG C, a byproduct sodium sulfate decahydrate is obtained through filtration, the mother solution is regulated to be neutral with a sodium hydroxide solution for recycled usage. The problems of high cost, low purity, difficult wastewater treatment and the like in the N-carbamylglutamic acid production process are solved, the product purity is up to 99% or above, and a feasible way is provided for industrial production of the N-carbamylglutamic acid.

The invention discloses a traditional Chinese medicinal feed additive containing N-carbamylglutamic acid, and its application. The above composition contains Radix Scutellariae, Radix Astragali, white peony root, honeysuckle flower, dried orange peel, licorice root and N-carbamylglutamic acid. The feed additive has the advantages of simple production technology, easily available raw materials, no hormones, improvement of the anti-stress capability of livestock, improvement of the immune function of the livestock, disease prevention, enhancement of the appetite of the livestock, and feed conversion rate improvement.

The invention relates to an anti-stress preparation for reducing fry transportation loss, as well as a preparation process and a use method thereof. The anti-stress preparation comprises vitamin C, taurine, r-aminobutyric acid and a traditional Chinese medicine extract, and is characterized by also comprising N-carbamylglutamic acid, wherein the weight of vitamin C is 20-30 parts, the weight of taurine is 25-40 parts, the weight of N-carbamylglutamic acid is 25-40 parts, the weight of r-aminobutyric acid is 10-15 parts, the weight of the traditional Chinese medicine extract is 5 parts, and theinsuffient rest parts are supplemented by anhydrous dextrose. Glucose has the effect of supplementing energy, so that the fries are kept vigorous. According to the anti-stress preparation, the knowningredients with relatively strong anti-stress effect on adult fish are matched with the traditional Chinese medicine extract (even glucose is added) to form a powdery compound, and the powdery compound is used as a culture water body for long-distance transportation of fish fries after being mixed with water, so that the survival rate of the fish fries subjected to oxygenated transportation within 48 hours can be increased by 20% or above.

The invention relates to a special feed for cyprinus carpio under alkaline water area culture conditions and a preparation method thereof and belongs to the technical field of cyprinus carpio feeds and preparation thereof. The feed is prepared from soybean meal, fish meal, middlings, bean oil, fish oil, phospholipid, choline chloride, sodium dihydrogen phosphate, mineral element premix, multivitamins, methionine, threonine, sodium butyrate, alpha-ketoglutaric acid and N-carbamylglutamic acid according to certain parts by mass. Through adding the sodium butyrate, the acid-base equilibrium of intestinal tracts can be changed, the activity of digestive enzymes is improved, the growth of probiotics is promoted to improve intestinal tract health, and growth is promoted. The alpha-ketoglutaric acid and the N-carbamylglutamic acid can convert ammonia resulting from catabolism of proteins into glutamine and arginine in a metabolism process, and nitrogen generated from metabolism is transferredinto amino acids again for reutilization, so that a toxic action on fish bodies caused by the ammonia and the nitrogen is reduced, and the utilization ratio of the nitrogen is increased; meanwhile, the generated glutamine and arginine can also be used for improving immunizing and oxidation resisting functions of organisms.

The invention relates to a pregnant sow feed additive and a preparation method thereof, and belongs to the field of a pig feed additive and a using method thereof. The pregnant sow feed additive comprises the following components in parts by weight: 6 to 15 parts of radix astragali, 4 to 12 parts of eucommia leaf, 5 to 10 parts of clove, 6 to 15 parts of rhizoma atractylodis, 8 to 12 parts of bighead atractylodes rhizome, 5 to 8 parts of chitosan, 6 to 10 parts of cinnamaldehyde, 8 to 12 parts of N-carbamylglutamic acid, and 20 to 40 parts of carrier. The pregnant sow feed additive can effectively improve the immunity and health state of sows, enhance the activity of ova, promote the combination of ova and sperm and the adhering of fertilized ova on the uterine wall, and increase the supply of oxygen and nutrients to the blood of placenta. Finally, the litter size and the newborn litter weight are increased, the individual uniformity is improved, the vitality of piglets and survival rate are improved; the pig farm PSY and farming benefits are increased; and the provided feed additive is safe, efficient, green, environmentally friendly and ecological.

The invention relates to an additive for promoting growth and development of young ruminants as well as a preparation method and an application of the additive. The additive for promoting growth and development of young ruminants comprises N-carbamylglutamic acid, fructooligosaccharide, complex enzyme, probiotics, decavitamin, calcium propionate, carrot powder and auxiliary materials. The additiveis used for feed young ruminants and can promote growth and development of young ruminants.

The invention provides a complete granulated feed capable of increasing slaughtering properties and meat quality of drylot-fed Tan sheep and a preparation method and application of the complete granulated feed. The complete granulated feed for Tan sheep comprises the following components of corn, soybean meal, cottonseed meal, alfalfa meal, soybean hulls, apple pomace, rumen-protected lysine, methionine, N-carbamylglutamic acid, saccharomyces cerevisiae cultures, stone powder, baking soda, conjugated linoleic acid, sodium chloride, a propanoic acid type mildewproof agent, montmorillonite, a sweetening agent, a trace element additive and composite vitamins. According to the complete granulated feed disclosed by the invention, a refined feed and a coarse feed are subjected to mixing and high-temperature granulation, so that the situation that the Tan sheep have dietary bias during foraging is avoided, and the food consumption of crude fiber raw materials of the Tan sheep is guaranteed. The rumen-protected lysine, the methionine, the N-carbamylglutamic acid and the like are added, so that amino acids required for growth of muscle of the Tan sheep can be met; the composite vitamins andthe trace elements are added, so that the complete granulated feed conforms to the physiological characteristics of the Tan sheep; and the conjugated linoleic acid additive is further added to the complete granulated feed and can be oxidized in bodies of the Tan sheep to produce volatile flavor substances, so that the mutton quality of the Tan sheep can be increased.

The invention discloses herd boar compound feed which comprises the following components in proportion by weight: 60-80 parts of corns, 6-18 parts of fermented bean meal, 10-25 parts of puffed soybeans, 1-7 parts of dry bamboo shoots, 2-8 parts of vegetable oil, 3-10[mu]g of organic trace elements, 1-15mg of a micro-ecological preparation, 0.1-1mg of an enzyme preparation, 2.5-7g of unsaturated fatty acids, 1-6mg of vitamin D3, 0.5-2mg of N-carbamylglutamic acid, 5-25mg of beta-carotenes, 5-15mg of vitamin E, 10-30g of tea residues, 150-350g of earthworm powder, 3-9g of potassium chloride, 0.3-8 parts of sodium chloride and 0.6-10 parts of lysine. The herd boar compound feed meets the demands of herd boar on proteins, mineral substances, fatty acids and vitamins, is relatively balanced in nutrition, and is capable of promoting digestion of the herd boar to the feed and absorption of nutrient substances, improving metabolism, enhancing immunity and improving quality of the herd boar.

The invention discloses a feed for promoting growth and development of fish larvae. The feed is characterized by being prepared from the following raw materials in parts by weight: 19-24 parts of rice bran, 23-26 parts of buckwheat bran, 36-38 parts of orange peel powder, 2-3 parts of red jujube peel, 20-22 parts of luffa leaf powder, 18-22 parts of freshwater mussel powder, 50-54 parts of pea protein powder, 4-5 parts of white fungus ultra tiny powder, 0.12-0.14 part of cellulase, 8-9 parts of licorice roots, 0.9-1.1 parts of N-carbamylglutamic acid chelating zinc and manganese methionine. According to the feed disclosed by the invention, carrot powder, a vitamin B1 solution, phosphatidylcholine and hyaluronic acid are stuffed into a honeycomb, so that vitamin granules are prepared; and an enveloping layer is arranged on the outer walls of the vitamin granules, so that the activity of nutrient granules is effectively protected, the digestive function of fish bodies is effectively improved, and the absorption of nutrient substances is promoted.

The invention discloses a creep feed. The creep feed is prepared from the following raw materials of puffed corn, corn, flour, puffed soybeans, super steam fish meal, 46% soybean meal, cane sugar, glucose, soybean oil, coconut oil, spray-dried dried egg yolk, yeast nucleotide, nonfat dry milk powder, whey powder, calcium propionate, calcium dihydrogen phosphate, multi-vitamins for piglets, montmorillonite, 98% lydine hydrochloride, DL-solid methionine, 98.5% L-threonine and a creep core material, wherein the creep core material consists of the following raw materials of table salt, composite organic trace elements, enveloping zinc oxide, a blood supplementing agent, a composite acidulant, a composite phagostimulant, a composite enzyme preparation, tryptophan, valine, N-carbamylglutamic acid, 50% choline chloride, an antioxidant, wheat hydrolyzed protein and puffed corn powder. Through adoption of the creep feed, the immune functions of the piglets can be quickly enhanced, generation ofdiseases is reduced, weaning stress is reduced, and food consumption of the piglets is increased. The invention further provides a preparation method of the creep feed. The creep feed is simple in technology and suitable for industrialized production.

The invention belongs to the technical field of aquaculture, and discloses a feed as well as a preparation method and application thereof. The feed comprises the following components: a camellia plant extract and additives, wherein the additives are composed of at least two selected from monocalcium phosphate, choline chloride, ethoxyquin, glutamine and N-carbamylglutamic acid. The feed also comprises an euphausia superba extract. The camellia plant extract and the additives are matched for use, so the prepared feed can remarkably improve the disease resistance and the survival rate of snakeheaded fish. The feed further contains the euphausia superba extract; the euphausia superba extract is rich in nutrient substances and further contains various active substances such as protein digestive enzymes, analogous mycotoxin amino acids and the like and has rich nutritional value; and as the euphausia superba extract is added into the prepared feed, the nutritional value of the feed can be effectively improved, the digestion function of the snakehead fish can be effectively promoted, and the rapid growth of the snakehead fish is thus facilitated.

The invention discloses an additive premix for improving the sow production performance. The additive premix comprises a carrier and an additive composition, wherein the additive composition is composed of 5-20 mg/kg of N-carbamylglutamic acid, 10-100 mg/kg of genistein, 10-50 mg/kg of daidzein, 0.5-1 mg/kg of folic acid, 10-100 mg/kg of vitamin E, 0.5-1 mg/kg of biotin, and 200-800 mg/kg of ferrous bisglycinate. The invention also provides a use method of the additive premix. The additive premix using the additive composition has better effects than an additive premix singly added with any one component, a use amount of each additive is reduced, and thereby the cost is saved. The additive premix provided by the invention can provide high-quality nutrition guarantee for the development ofembryos, placentas and fetuses in sows, significantly increases the total litter size and live litter size of the sows, also improves the newborn litter weight, newborn individual weight and placentaweight to a certain extent, and thereby effectively improves the production performance of the sows.

The invention discloses a method for improving the reproductive performance of sheep. The method includes the following steps that mating is carried out by using insemination methods such as natural mating, vaginal artificial insemination, cervix artificial insemination and laparoscopic uterine horn insemination, the day of mating is counted as the zeroth pregnancy day, and a feed containing 0.05%-2% dietary N-carbamylglutamic acid is started to feed from the 0-40th day of pregnancy. The action principle of NCG is fully used, the total number of lambs per nest of ewe is increased by adding NCGin the early pregnancy to increasing the NO concentration and iNOS enzyme activity in the systemic circulation of the ewe, reducing the plasma ammonia concentration and reducing embryonic death, andthe number of live lambs of nest breeding is increased by improving the intrauterine environment so as to improve the reproductive performance of the ewe. The N-carbamoylglutamic acid added in the method is an amino acid derivative, is a safe and reliable feed additive and has no toxic and side effects, the addition method is simple, and the effect of improving the reproductive performance of sheep is obvious.