A kind of mugwort leaf extract and its preparation method and application

A wormwood leaf extract and the technology of the extract, which are applied in the field of plant-derived antibacterial preparations, can solve the problems of low recurrence rate, complex formula and the like, and achieve the effects of simple preparation, expanded application scope and difficult drug resistance.
CN113713003BActive Publication Date: 2022-07-29湖北嘉绘生物科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
湖北嘉绘生物科技有限公司
Publication Date
2022-07-29

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Abstract

The invention discloses an extract of Artemisia argyi, a preparation method thereof, and application of an antibacterial agent for dermatophytes, belonging to the technical application field of plant-derived antibacterial preparations. The antibacterial agent is the wormwood leaf extract obtained by ultrasonic extraction (5-75% ethanol) or ethanol reflux extraction with Chinese herbal medicine argyi leaf as raw material. Dermatophytes are highly inhibited. After being separated and purified by macroporous adsorption resin, the 40-95% ethanol fractions have different degrees of inhibitory activity against dermatophytes, and the 95% ethanol fraction is the most significant. At the same time, the main chemical compositions of the 95% ethanol separated fractions are iszelanin, emodin methyl ether, vitexin, and brown cyanidin. The invention can effectively inhibit dermatophytes, has the advantages of safety, high efficiency and low toxicity and side effects, and provides a new drug source for the prevention and treatment of dermatophytes such as hand and tinea pedis.
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Description

technical field

[0001] The invention belongs to the technical application field of plant-derived antibacterial preparations, and particularly relates to a natural antibacterial agent based on argyi leaf extract and a preparation method and application thereof. Background technique

[0002] Dermatophytosis is a skin infection caused by the infection of human or animal skin, fur, and deck by dermatophytes, which are pro-colloid proteins, and can be infected on the head, hands, and feet. Dermatophytosis is widely prevalent all over the world, and is more prevalent in tropical and subtropical regions. The incidence in my country is also quite high. The clinical manifestations are mainly erythema, blisters, pustules and other skin lesions, with obvious itching. Different levels of symptoms appear, which troubles a large number of people. At present, a large number of studies have shown that the pathogenic bacteria of dermatophytes such as tinea corporis and tinea pedis are roughl...

Claims

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