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No-clean antibacterial peptide hand sanitizer

A technology of antibacterial peptide and hand sanitizer, which is applied in the field of daily chemicals, can solve the problems of degradability not as good as ethanol, accelerate skin drying, hand skin dryness, etc., and achieve the effects of simple preparation method, reduced usage, and strong antibacterial effect

Inactive Publication Date: 2021-12-21
SHAANXI NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, one of the main formulas of disposable antibacterial / antibacterial hand sanitizers is to use ethanol, and the ethanol content generally needs to exceed 70% to have a good bactericidal effect, and the cleaning effect of ethanol is not strong, so it cannot take into account the effects of cleaning and sterilization , and high concentration of ethanol will cause dry and rough skin on hands and accelerate skin aging
The second formula uses quaternary ammonium salts as the main component. Quaternary ammonium salts are cationic surfactants, which have certain decontamination properties and good bactericidal effects. The disadvantage is that the degradability is generally not as good as ethanol
[0005] Existing antibacterial / antibacterial hand sanitizers cannot satisfy consumers’ pursuit of epidemic prevention, but adding natural antibacterial / antibacterial ingredients to hand sanitizers is not only safe and harmless to the human body, but also the product is easy to degrade, more green, and will not pollute the ecology Environment, satisfying consumers' safe and green consumption concept

Method used

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  • No-clean antibacterial peptide hand sanitizer
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  • No-clean antibacterial peptide hand sanitizer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] The mass percent of the disposable antibacterial peptide hand sanitizer of the present embodiment consists of: carbomer 0.2%, antibacterial peptide 0.00025%, benzalkonium chloride 0.02%, didecyldimethylammonium chloride 0.01%, coconut oil diethanol Amide 6501 2.4%, alkyl polyglycoside APG 1.8%, glycerin 0.5%, white and polysaccharide 0.1%, rose essential oil 0.05%, triethanolamine 0.05%, deionized water added to 100%. The preparation method is as follows: add carbomer to deionized water, stir with a homogeneous mixer at room temperature, make it fully swell overnight, and prepare a gel matrix after the swelling is complete; then add alkyl polyglycoside APG and coconut oil two Add ethanolamide 6501 into the gel matrix and stir evenly; then under the condition of sterile preparation, first add benzalkonium chloride and didecyldimethylammonium chloride into the gel matrix, then add rose essential oil, glycerin , white and polysaccharide, stir evenly, then add antibacterial...

Embodiment 2

[0071] The mass percent of the disposable antibacterial peptide hand sanitizer of the present embodiment consists of: carbomer 0.15%, antibacterial peptide 0.00020%, benzalkonium chloride 0.01%, didecyldimethylammonium chloride 0.01%, coconut oil diethanol Amide 6501 2.7%, alkyl polyglycoside APG 0.9%, glycerin 0.3%, white and polysaccharide 0.2%, rose essential oil 0.01%, triethanolamine 0.04%, deionized water added to 100%. The preparation method is as follows: add carbomer to deionized water, stir with a homogeneous mixer at room temperature, make it fully swell overnight, and prepare a gel matrix after the swelling is complete; then add alkyl polyglycoside APG and coconut oil two Add ethanolamide 6501 into the gel matrix and stir evenly; then under the condition of sterile preparation, first add benzalkonium chloride and didecyldimethylammonium chloride into the gel matrix, then add rose essential oil, glycerin , white and polysaccharide, stir evenly, then add antibacteria...

Embodiment 3

[0073] The mass percent of the disposable antibacterial peptide hand sanitizer of the present embodiment consists of: carbomer 0.25%, antibacterial peptide 0.00030%, benzalkonium chloride 0.1%, didecyldimethylammonium chloride 0.05%, coconut oil diethanol Amide 6501 2.4%, alkyl polyglycoside APG 1.8%, glycerin 0.2%, white and polysaccharide 0.2%, rose essential oil 0.03%, triethanolamine 0.06%, deionized water added to 100%. The preparation method is as follows: add carbomer to deionized water, stir with a homogeneous mixer at room temperature, make it fully swell overnight, and prepare a gel matrix after the swelling is complete; then add alkyl polyglycoside APG and coconut oil two Add ethanolamide 6501 into the gel matrix and stir evenly; then under the condition of sterile preparation, first add benzalkonium chloride and didecyldimethylammonium chloride into the gel matrix, then add rose essential oil, glycerin , white and polysaccharide, stir evenly, then add antibacterial...

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Abstract

The invention discloses a no-clean antibacterial peptide hand sanitizer, which is prepared from the following components in percentage by mass: 0.15%-0.25% of carbomer, 0.00020%-0.00030% of antibacterial peptide, 0.01%-0.1% of benzalkonium chloride, 0.01%-0.1% of didecyl dimethyl ammonium chloride, 2.00%-5.00% of a surfactant, 0.40%-0.60% of a humectant, 0.01%-0.05% of essential oil, 0.04%-0.06% of a pH regulator and the balance of deionized water; the amino acid sequence of the antibacterial peptide is shown as SEQ ID NO:1; the surfactant is a mixture of alkyl polyglucoside APG and coconut oil diethanolamide 6501; and the humectant is a mixture of glycerol and rhizoma bletillae polysaccharide. The hand sanitizer disclosed by the invention has broad-spectrum antibacterial activity, is safe and free from washing; the use amount of the antibacterial peptide is reduced to a great extent; the cost is saved; meanwhile, a relatively strong antibacterial effect is exerted; and the preparation method is simple and suitable for large-scale industrial production.

Description

technical field [0001] The invention belongs to the technical field of daily chemicals, and in particular relates to a no-wash antibacterial peptide hand sanitizer. Background technique [0002] In the face of repeated outbreaks and new infectious diseases, the best "treatment" means is "prevention and control". One of the most effective measures to cut off the spread of pathogens is to pay attention to personal hygiene, especially hand hygiene. Compared with traditional hand soap, the biggest advantage of hand sanitizer is that "every drop is new", and it has an absolute advantage in avoiding being called a secondary pollution source; at the same time, it has less damage to the skin, less natural consumption, and practicality. Strong and other advantages. [0003] At present, the bactericides commonly used in antibacterial / antibacterial hand sanitizers are mainly phenols (p-chloro-m-xylenol, phenylphenol, etc.), quaternary ammonium salts (benzalkonium chloride, etc.), guan...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/92A61K8/365A61K8/41A61K8/73A61K8/81A61K8/34A61K8/42A61K8/60A61Q19/10A61Q17/00
CPCA61K8/8147A61K8/64A61K8/416A61K8/922A61K8/345A61K8/73A61K8/41A61K8/365A61K8/42A61K8/602A61Q19/10A61Q17/005A61K2800/596
Inventor 孙燕张许林陈靖怡向南姝曹苗苗屈可谢瑜李治
Owner SHAANXI NORMAL UNIV
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