Continuous microfluidic biochip design method considering fluid operation and channel storage

Abstract

The invention relates to a continuous micro-fluidic biochip design method considering fluid operation and channel storage, which comprises the following steps: S1, calculating the priority of each operation according to a time sequence diagram, and calculating the priority of each operation through a binding and scheduling algorithm based on volume perception; obtaining an allocated component table and a group of transportation task tables considering fluid transportation, removal and channel storage; s2, according to the component table, distributing the components to exact positions of the biochip based on a memory search layout algorithm; and S3, according to the layout result and the transportation task table, establishing effective connection between the fluid ports and the assemblies by using a flow path driven wiring algorithm, and arranging an receivable flow channel for the storage task to complete the continuous micro-fluidic biochip architecture design. According to the invention, all transportation tasks of the chip can be executed without conflicts, and the storage fluid can be effectively placed in the selected flow channel.

Description

technical field [0001] The invention relates to the technical field of integrated circuit computer aided design, and relates to a continuous microfluidic biological chip design method considering fluid operation and channel storage. Background technique [0002] Continuous-Flow Microfluidic Biochips (CFMBs) have changed the traditional biochemical assay procedures due to their high execution efficiency and high accuracy. Continuous microfluidic biochips reduce the volume of fluid required for biochemical assays to nanoliter levels through miniaturized fluid operations, which can save valuable samples and reagents and reduce experimental costs. [0003] Typically, continuous microfluidic biochips use dedicated memory to store intermediate fluids generated during the execution of biochemical assays. However, this storage method has the following disadvantages: 1) the capacity of the storage unit is limited; 2) the storage location is fixed; 3) the dedicated memory needs to oc...

AI Technical Summary

Problems solved by technology

However, this storage method has the following disadvantages: 1) the capacity of the storage unit is limited; 2) the fixed storage location; 3) the special memory needs to occupy a larger chip area; 4) the limited bandwidth

Larger storage fluid volumes require longer flow channels, which are more prone to physical defects such as blockages and leaks

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