Method for judging degree of myelohyperplasia

Abstract

The invention relates to a method for judging the degree of myelohyperplasia, the method comprises the following steps: when a bone marrow smear reaches a specified position, starting a grey-spot camera, and automatically scanning the whole bone marrow smear by an electronic eyepiece; storing all the images of the bone marrow smear collected by the electronic eyepiece for later use; repeatedly collecting a large number of image samples of the bone marrow smear; dividing the collected picture samples according to the thickness and the uniformity of bone marrow cells, and generating an algorithm for calculating the thickness and the uniformity of the bone marrow smear according to the divided pictures; collecting a whole picture of the bone marrow smear again; calculating the thickness and the uniformity of the bone marrow smear by using an algorithm, and selecting a region with moderate thickness and uniform distribution of bone marrow cells in the bone marrow smear; respectively calculating the area of all mature red blood cells and the area of nucleated cells in the frame selection area, calculating the area ratio of the mature red blood cells to the nucleated cells, and judging the degree of myelohyperplasia according to the area ratio of the red blood cells to the nucleated cells in the bone marrow.

Description

Technical field [0001] The present invention is in the medical diagnostic field of artificial intelligence, in particular myeloproliferative extent relates to a method for determining. Background technique [0002] Bone marrow cells morphological examination of blood pathology is one of the key diagnostic tool, often used to diagnose a variety of diseases, including leukemia, multiple myeloma, lymphoma, anemia and pancytopenia, etc., and the degree of bone marrow hyperplasia judge is bone marrow examination in an important element for high proliferative (e.g., various leukemias) with low proliferative (e.g., aplastic anemia) diagnosis of diseases of great value. Currently on the degree of proliferation of bone marrow evaluation method to use more five classification of Chinese Institute of Hematology and Medical in uniform thickness smear region based on the number of nucleated red blood cells and mature than estimated, divided hyperplasia hyperactive, hyperplastic was active, hy...

AI Technical Summary

Problems solved by technology

This method has a large degree of dispersion between each level of the reference interval, and it is difficult to grasp the critical value. At present, most bone marrow smears use manual microscopic examination, and the number of red blood cells and nucleated cells is collected and counted manually, so it is easily affected by subjective factors.

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