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An alcohol-soluble and moisturizing natural three-star gum, leave-in sanitizing gel and application

A technology of disinfectant gel and sanzan gel, which is applied in the fields of disposable disinfectant gel and natural sanzan gel, and can solve problems such as compatibility, poor stability, and easy flocculation

Active Publication Date: 2022-08-05
NANKAI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, gel thickeners such as cellulose and carbomer have poor compatibility and stability with disinfectants such as ethanol and isopropanol.
At present, there are few natural product polysaccharides used as gelling agents and thickeners for the preparation of hand sanitizer gels. The main reason is that natural gel thickeners are insoluble in fat-soluble reagents such as ethanol and isopropanol, and are easy to flocculate to form precipitates.

Method used

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  • An alcohol-soluble and moisturizing natural three-star gum, leave-in sanitizing gel and application
  • An alcohol-soluble and moisturizing natural three-star gum, leave-in sanitizing gel and application
  • An alcohol-soluble and moisturizing natural three-star gum, leave-in sanitizing gel and application

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Experimental program
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preparation example Construction

[0055] The present invention provides a preparation method of the disposable disinfectant gel, comprising the following steps:

[0056] 1) the natural Sanzan gum is dissolved in water to obtain a Sanzan gum solution;

[0057] 2) mixing Sanzan gum solution with disinfectant and cation in step 1) to obtain mixed solution 1;

[0058] 3) ethanol and fragrance are mixed to obtain mixed solution 2;

[0059] 4) mixing the mixed solution 1 in step 2) and the mixed solution 2 in step 3), heating at 75-90° C., and cooling to obtain a no-clean sanitizing gel;

[0060] There is no time sequence restriction between steps 1) to 2) and step 3).

[0061] In the present invention, the natural Sanzan gum is dissolved in water to obtain a Sanzan gum solution.

[0062] In the present invention, the mass percentage content of the prepared Sanzan gum solution is preferably 0.15-0.3%, more preferably 0.2-0.25%.

[0063] After obtaining the Sanzan gum solution, the present invention mixes the San...

Embodiment 1

[0073] Ethanol solubility test of Sanzan gum

[0074] 1) Using Sphingomonas T-3 (CGMCC No. 10150) to ferment the original high acyl triazine gum, and using Sphingomonas NXdP (CGMCC No. 15406) ​​to ferment the transparent type high acyl triamcinolone gum , using Sphingomonas T-4 (CGMCC No.22948) to produce low acyl triazine gum;

[0075] 2) Take original high acyl samara gum, transparent high acyl samara gum and low acyl samara gum to prepare aqueous solutions with concentrations of 0.02%, 0.1%, 1% and 3% respectively;

[0076] 3) Mix the above-prepared Sanzan glue aqueous solutions of different concentrations in a volume ratio of 1:1 and 0.1:1, and stir evenly. Observing the inside of the tube, it was found that there was no precipitation in each tube, indicating that the Sanzan gum solution could be miscible with ethanol and had alcohol-soluble properties.

[0077] (4) The above-mentioned Sanzan glue aqueous solution is heated at 90° C. for 10-30 minutes, and then cooled to...

Embodiment 2

[0079] Determination of moisturizing properties of natural product polysaccharide Sanzan gum, the specific method is as follows:

[0080] (1) weigh each 3 parts of 3 kinds of natural Sanzan gum, sodium hyaluronate, glycerin in the embodiment 1 of 0.5g in weighing bottle;

[0081] (2) Add 0.2g of distilled water, and after the sample fully absorbs water, place it in a desiccator equipped with silica gel, place it at room temperature, and weigh it after 3, 6, 9, 18, 21, and 24 hours, respectively, and calculate the average of 3 times. value, according to formula I to calculate the moisturizing rate:

[0082] Moisturizing rate (%)=H n / H o ×100% Formula I

[0083] Among them, H n Moisture quality of samples at different times (unit: g); H o is the initial moisture mass of the sample (unit: g).

[0084] In Example 1, the three kinds of Sanzan gums have the same moisturizing performance as hyaluronic acid, and after being placed for 24 hours, they have a moisturizing rate of ...

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Abstract

The invention provides a natural sanzan gum with alcohol solubility and moisturizing properties, a no-wash disinfection gel and application, and belongs to the technical field of hygiene and disinfection products. The natural Sanzan gum provided by the invention is a natural product polysaccharide produced by Sphingomonas, has the characteristics of alcohol solubility, moisturizing, gelling, thickening, emulsifying and the like, and can be used as a natural gel thickening agent It is used in hand-free sanitizing gel, cosmetics and other products, and has the characteristics of green, safe and stable. The disposable disinfectant gel containing natural Sanzan gum provided by the invention is free of hand washing, can kill pathogenic microorganisms, has the characteristics of disinfection and sterilization, skin care, greenness, safety, comfort and the like, and is suitable for medical personnel and families. New hand sanitizer gel.

Description

technical field [0001] The invention belongs to the technical field of sanitation and disinfection products, and in particular relates to a natural Sanzan gum with alcohol solubility and moisturizing properties, a disposable disinfection gel and applications. Background technique [0002] Disposable disinfectant gel is simple to use and has remarkable effect, and can effectively remove bacteria on hands. It is a disinfection product with ethanol, biguanide disinfectant, quaternary ammonium salt disinfectant, etc. as the main active ingredients. Enteric pathogenic bacteria, pyogenic coccus, pathogenic yeast and common bacteria in hospital infections, suitable for surgical hand disinfection and hygienic hand disinfection. Disposable sanitizing gel is widely used because it can effectively eliminate hand germs without washing with water, and it is easy to carry and use. [0003] At present, the disposable disinfectant gels on the market are mainly composed of gel thickeners, d...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/73A61K8/99A61K8/19A61K8/41A61K8/43A61K8/04A61Q19/10A61Q17/00A61Q19/00
CPCA61K8/73A61K8/99A61K8/19A61K8/416A61K8/43A61K8/042A61Q19/10A61Q17/005A61Q19/00A61K2800/48
Inventor 马挺吴萌萌李国强石壮壮明月
Owner NANKAI UNIV
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