Kit for predicting urine metabolite characteristics of premature delivery and predicting premature delivery

A technology of metabolites and kits, applied in the field of personalized medicine, can solve problems such as the risk prediction of premature birth without metabolism, and achieve the effect of eliminating discomfort and reducing risks

Active Publication Date: 2022-02-15
天津云检医学检验所有限公司 +1
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  • Abstract
  • Description
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Problems solved by technology

[0003] Despite the current increase in understanding of the biology of metabolic systems in normal, term, a

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  • Kit for predicting urine metabolite characteristics of premature delivery and predicting premature delivery
  • Kit for predicting urine metabolite characteristics of premature delivery and predicting premature delivery
  • Kit for predicting urine metabolite characteristics of premature delivery and predicting premature delivery

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[0022] Next, the technical solutions in the embodiments of the present invention will be described in connection with the drawings of the embodiments of the present invention, and it is understood that the described embodiments are merely the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art are in the range of the present invention without making creative labor premise.

[0023] In view of the high incidence and mortality rate of premature birth and premature infants, it is very necessary to identify high-risk pregnans and implement interventions as soon as possible, the inventors have been used for long-term research, and urine metabolites can be used for premature prediction.

[0024] The urine metabolite characteristics of the embodiment of the present invention include at least one mass: m / z 112.040, m / z115.087, m / z 125.071, M / Z 129.0...

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Abstract

The invention discloses a kit for predicting urine metabolite characteristics of premature delivery and predicting premature delivery and a premature delivery prediction kit. Premature delivery can be predicted through the urine metabolite characteristic, so medical personnel can take corresponding measures according to a prediction result to reduce the risk of premature mothers and postnatal newborn disease infants, and meanwhile, the adopted kit can adopt urine of a subject as a detection sample, so the discomfort of the subject during blood sample collection is eliminated.

Description

technical field [0001] The invention relates to the technical field of personalized medicine, in particular to a urine metabolite feature for predicting premature delivery and a premature delivery prediction kit. Background technique [0002] Premature delivery (PTB, Premature Delivery) is one of the important causes of perinatal death, with an incidence rate of 5% to 15%. Generally, delivery between 28 weeks of gestation (196 days) and 37 weeks of gestation (259 days) is defined as premature birth. During this period, newborns with a birth weight of 1000-2499 g and immature organs of the body are premature babies. During pregnancy, it is also important to make reasonable predictions about preterm birth, a pathological consequence of pregnancy and a major global health problem, as preterm infants are at higher risk of long-term medical and neurodevelopmental sequelae. [0003] Despite the current increase in understanding of the biology of metabolic systems in normal, term,...

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Application Information

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IPC IPC(8): G01N30/72G01N30/02
CPCG01N30/72G01N30/02
Inventor 陈利民
Owner 天津云检医学检验所有限公司
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