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COMPOSITION FOR LOWERING BLOOD GLUCOSE LEVEL, REDUCING BLOOD HEMOGLOBIN Alc CONTENT, OR INCREASING BLOOD HDL-CHOLESTEROL CONTENT

A technology of glucose concentration and hemoglobin is applied in the field of compositions for reducing blood glucose concentration, reducing blood hemoglobin Alc amount or increasing blood HDL-cholesterol amount, which can solve problems such as increased disease risk and achieve improvement in lipids. Metabolism, lowering the effect of glucose concentration

Pending Publication Date: 2022-02-18
เฮ้าส์ เวลล์เนสส์ ฟูดส์ คอร์ปอเรชั่น
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

It is also known that when hypocholesterolemia occurs, cholesterol accumulates in blood vessels and the risk of arteriosclerotic diseases increases (Non-Patent Document 2)

Method used

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  • COMPOSITION FOR LOWERING BLOOD GLUCOSE LEVEL, REDUCING BLOOD HEMOGLOBIN Alc CONTENT, OR INCREASING BLOOD HDL-CHOLESTEROL CONTENT
  • COMPOSITION FOR LOWERING BLOOD GLUCOSE LEVEL, REDUCING BLOOD HEMOGLOBIN Alc CONTENT, OR INCREASING BLOOD HDL-CHOLESTEROL CONTENT
  • COMPOSITION FOR LOWERING BLOOD GLUCOSE LEVEL, REDUCING BLOOD HEMOGLOBIN Alc CONTENT, OR INCREASING BLOOD HDL-CHOLESTEROL CONTENT

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Experimental program
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Embodiment

[0235] 1. The preparation method of turmeric extract

[0236] The turmeric extract is prepared by extracting the rhizome part of turmeric (Curcuma longa) with water and drying the obtained extract by heating under reduced pressure to remove water. The amounts of curcumonol A (TA) and curcumonol B (TB) in the turmeric extract were measured by LC / MS, and the amounts of bisabolcurcuminol and curcumin were measured by HPLC.

[0237] 2. Test food

[0238] The test food was a tablet containing 86.5 μg of TA, 24.7 μg of TB, 400 μg of bisabolcurcumol, and 471 μg of curcumin per three tablets of the turmeric extract. The food to be tested was prepared by mixing turmeric extract, excipients, brighteners, coloring agents, and manufacturing agents (fine-particle silicon dioxide, sucrose fatty acid ester) and then tableting it into tablets.

[0239] The placebo food is a tablet prepared by replacing the turmeric extract of the above-mentioned test food with an excipient.

[0240] 3. Det...

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Abstract

One or more embodiments of the present invention provide a composition for improving lipid metabolism or carbohydrate metabolism, said composition containing a component derived from turmeric. One or more embodiments of the present invention pertain to a composition for lowering blood glucose level, reducing blood hemoglobin Alc content or increasing blood HDL-cholesterol content, a composition for treating or preventing metabolic syndrome or a composition for improving lipid metabolism or carbohydrate metabolism, said composition containing at least one selected from turmeronol A, turmeronol B and bisacurone as an active ingredient. The aforesaid composition can contain turmeronol A and turmeronol B in a total amount of 20 [mu]g or more per daily intake, turmeronol A in an amount of 17 [mu]g or more per daily intake, turmeronol B in an amount of 5 [mu]g or more per daily intake, and bisacurone in an amount of 80 [mu]g or more per daily intake.

Description

technical field [0001] One or more embodiments of the present invention relate to a composition for lowering blood glucose concentration, lowering blood hemoglobin A1c level, or increasing blood HDL-cholesterol level. [0002] One or more embodiments of the present invention also relate to a composition for treating or preventing metabolic syndrome. [0003] One or more embodiments of the present invention also relate to a composition for improving lipid metabolism or glucose metabolism. Background technique [0004] It is known that blood sugar and hemoglobin Alc (HbAlc) are indicators for the diagnosis of diabetes, and an increase in their blood concentration is considered to be one of the causes of microvascular or macrovascular lesions, which increases the risk of various diabetic complications. Morbidity risk (non-patent literature 1). [0005] In addition, high-density lipoprotein (High Density Lipoprotein (HDL)) cholesterol takes on the role of transporting choleste...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/12A61P3/10A61P3/06A61K36/9066
CPCA61K31/12A61P3/10A61P3/06A61K36/9066A61K2300/00A61P9/10A61P3/04A61K31/122
Inventor 内尾隆正室山幸太郎川崎健吾室崎伸二
Owner เฮ้าส์ เวลล์เนสส์ ฟูดส์ คอร์ปอเรชั่น
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