Heavy metal probability risk assessment method and system for rhizome traditional Chinese medicine curcuma zedoary

Abstract

The invention relates to a rhizome traditional Chinese medicine curcuma zedoary heavy metal probability risk assessment method and system. The method comprises the following steps: establishing a chronic exposure evaluation model; acquiring the concentration of to-be-assessed heavy metals in the to-be-assessed traditional Chinese medicine and the intake and intake frequency of the to-be-assessed traditional Chinese medicine by adopting an empirical distribution fitting method, and calculating the daily exposure of the to-be-assessed heavy metals in the to-be-assessed traditional Chinese medicine by adopting a chronic exposure assessment model, and calculating a chronic exposure non-carcinogenic risk entropy, a combined non-carcinogenic risk entropy, a chronic carcinogenic risk entropy and a combined carcinogenic risk entropy of the to-be-assessed heavy metal in the to-be-assessed traditional Chinese medicine, and performing risk assessment accordingly. According to the method, a method for estimating the exposure quantity of various heavy metals in the rhizome traditional Chinese medicine and a method for evaluating non-carcinogenic and carcinogenic probability risks are provided, the purpose of quantifying uncertainty existing in the evaluation process is achieved through random simulation sampling, and the accuracy of risk evaluation is improved.

Description

technical field [0001] The invention relates to the technical field of risk assessment of traditional Chinese medicines, in particular to a method and a system for assessing the probability risk of heavy metals in rhizome traditional Chinese medicine Curcuma radix. Background technique [0002] China is rich in resources of Chinese herbal medicine. Because of its unique curative effect and few side effects, traditional Chinese medicine is widely used in China and many other countries to treat various diseases, and it has received more and more attention. The rhizome Chinese medicinal materials are the medicinal materials of underground stems or underground stems with a few roots, including many kinds of traditional Chinese medicines such as Polygonatum vulgaris, Curcuma, Morinda officinalis and black medicine. Curcuma curcuma is widely used in traditional Chinese medicine prescriptions because of its pharmacological effects such as promoting blood circulation and removing bl...

AI Technical Summary

Problems solved by technology

In the assessment of exposure to heavy metals in traditional Chinese medicines, due to the differences in the use of traditional Chinese medicines in the population, the persistence of the range of traditional Chinese medicines used, the complexity of drug formulations, and the diversity of forms and dosage forms, the results of point assessments cannot take into account the variability in health risks. The problem is that the results are relatively rough and the evaluation accuracy is low, and the evaluation results cannot protect high-end exposed groups

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