Nasal cavity nursing spray as well as preparation method and application thereof

Abstract

The invention relates to a nasal cavity nursing spray. According to the nasal cavity nursing spray, one or more of xyloglucan and tamarind gum are adopted as effective components playing a physical barrier role, allergens can be effectively blocked, meanwhile, the swing frequency of cilia is not affected, no obvious adhesion feeling exists in the nasal cavity in the using process, the comfort is high, and the nasal cavity nursing spray is suitable for being used in the nasal cavity. Meanwhile, the nasal cavity nursing spray disclosed by the invention can also contain sodium cromoglycate as an anti-allergic reaction medicine, can inhibit the adverse reaction of an allergic reaction medium to tissues, has good prevention and treatment effects on quick-onset and delayed-onset allergic reactions, and can have a good prevention effect on allergic rhinitis when being used together with a blocking agent. The invention also relates to a preparation method and application of the nasal cavity nursing spray.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a nasal cavity care spray and its preparation method and application. Background technique [0002] Allergic rhinitis (AR) is a non-infectious chronic inflammatory disease of nasal mucosa mainly mediated by immunoglobulin E (IgE) after the body is exposed to allergens. A large number of epidemiological surveys at home and abroad have shown that the prevalence of AR has increased significantly in recent years, resulting in a large disease burden. AR has become a major chronic inflammatory disease of the respiratory tract, which has a serious impact on the quality of life of patients and social economy. [0003] The main treatment methods for AR include: allergen avoidance, drug therapy, immunotherapy, and surgical treatment. The "Guidelines for the Diagnosis and Treatment of Allergic Rhinitis" issued by the Otorhinolaryngology Branch of the Chinese Medical Association clearly s...

AI Technical Summary

Problems solved by technology

Yet the product of the present invention has following shortcoming: 1, this product is a gel state blocking agent, is applied in nasal cavity, because it has bigger stickiness, may adhere to each other with nasal mucous membrane cilia, thereby makes the swing of nasal mucous membrane cilia The frequency is reduced, which affects the function of nasal mucosa cilia to filter out impurities in the air and prevent particles such as dust particles from entering the respiratory tract; 2. The gel-state blocker is completely adhered to the nasal cavity during use, and the nasal cavity feels sticky during use. less comfortable

Yet, the shortcoming of product of the present invention is: product oiliness is bigger, influences cilia vibration frequency, comfortableness is not good

The disadvantage of the present invention is that it does not contain barrier components and cannot avoid continuous contact of nasal mucosa with allergens

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