Method for preparing genistein

A genistein and strain technology, applied in the field of microorganisms, can solve the problems of expensive equipment, high production cost and high technical requirements
CN114350722AActive Publication Date: 2022-04-15INST OF AGRO FOOD SCI & TECH CHINESE ACADEMY OF AGRI SCI

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF AGRO FOOD SCI & TECH CHINESE ACADEMY OF AGRI SCI
Publication Date
2022-04-15

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Abstract

The invention relates to a method for preparing genistein, which can increase the content of genistein by culturing streptomyces lateritius through a liquid culture medium containing soybean meal. The method comprises the following steps: by using a liquid fermentation culture medium, adding cultured streptomyces lateriorubidus CGMCC No.21851 at 29 DEG C, fermenting for 3 days, and extracting, concentrating, separating and purifying a fermentation product, thereby obtaining the genistein. According to the method, it is found for the first time that the streptomyces lateritius CGMCC No.21851 can convert genistin into genistein, compared with similar streptomyces lateritius, the streptomyces lateritius has new performance, and the used raw material soybean meal is rich in resource, low in price and easy to obtain. According to the method, the utilization rate of the soybean byproducts is increased, and a new method and way are provided for production and preparation of genistein.
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Description

technical field

[0001] The invention relates to the technical field of microorganisms, in particular to a method for preparing genistein, which is used to obtain genistein from fermentation products. Background technique

[0002] Genistein, also known as genistein, genistein, and 5,7,4′-trihydroxyisoflavone, is the main active ingredient of soybeans and soybean products, and is also the most active and functional of isoflavones A sort of. Genistein has estrogen-like effects and has potential beneficial effects on major human diseases, including anti-inflammation, anti-oxidation, anti-osteoporosis, anti-inflammation, labor pain, lowering uric acid, regulating blood lipids, etc. Therefore, the extraction and purification of genistein have attracted more and more attention.

[0003] In the prior art, CN113930466A discloses genistein derived from Bacillus spp. and provides its preparation method, but the yield of genistein is not high. CN112358461A discloses a method for extr...

Claims

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