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Medicinal and edible traditional Chinese medicine composition for treating functional diarrhea

A technology of medicine and food homology and composition, applied in the field of traditional Chinese medicine composition of medicine and food homology, to achieve the effect of alleviating the effect, improving disease symptoms, and having no toxic and side effects

Pending Publication Date: 2022-05-06
BEIJING UNIV OF CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, from the perspective of FDr's long disease course and recurrent disease characteristics, there are certain limitations in the treatment effect of western medicine.

Method used

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  • Medicinal and edible traditional Chinese medicine composition for treating functional diarrhea
  • Medicinal and edible traditional Chinese medicine composition for treating functional diarrhea
  • Medicinal and edible traditional Chinese medicine composition for treating functional diarrhea

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1 Chinese medicine composition of the present invention is to the effect of functional diarrhea rat pharmacodynamic effect and the impact of colon tissue aquaporin (AQP3 and AQP8) expression

[0019] 1. Materials and methods

[0020] 1.1 Experimental animals

[0021] Male SPF grade Wistar rats, 3 weeks old, weighing 90-120 g, were purchased from Beijing Weitong Lihua Technology Co., Ltd., license number SCXK (Beijing) 2017-0033. They were raised in the SPF level experimental animal center of Beijing University of Traditional Chinese Medicine, with a room temperature of 18-25°C and a relative humidity of 50%-60%. Rats started the experiment after one week of adaptive feeding, and had free access to food and water during the period. The experiment was approved by the Experimental Animal Ethics Committee of Beijing University of Traditional Chinese Medicine (No.: BUCM-4-2018101002-4031).

[0022] 1.2 Reagents and equipment

[0023] D-xylose determination kit...

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Abstract

The invention relates to a medicinal and edible traditional Chinese medicine composition for treating functional diarrhea, which belongs to the technical field of traditional Chinese medicines and comprises the following raw material medicines: coix seed, Chinese yam, poria cocos, white hyacinth bean, platycodon grandiflorum, lotus seed, honey-fried licorice root, pericarpium citri reticulatae and Chinese date. The medicine composition is prepared from medicinal and edible traditional Chinese medicinal materials, has no toxic or side effect and can be taken for a long time. Animal experiment research proves that the traditional Chinese medicine composition can promote intestinal water reabsorption by regulating expression of aquaporin AQP3 and AQP8, so that the disease symptom of functional diarrhea is effectively improved, and the physiological function of the intestinal tract is recovered.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition with the same source of medicine and food for treating functional diarrhea, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Functional diarrhea (Funcyional Diarrhea, FDr) is a common chronic gastrointestinal disease, the clinical symptoms are "more than 25% of the defecation is not accompanied by obvious abdominal pain or abdominal distension". The course of the disease is protracted and prone to repeated attacks, which seriously affects the quality of life of patients and increases the economic burden of the society to a certain extent. At present, Western medicine mostly treats FDr by improving gastrointestinal function or microecological preparations, cooperating with patients to establish reasonable diet and work and rest habits, and relieving patients' stress, anxiety and other mental stress. The treatment method of Western medici...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P1/12
CPCA61K36/8994A61K36/8945A61K36/076A61K36/48A61K36/346A61K36/62A61K36/484A61K36/752A61K36/725A61P1/12A61K2300/00
Inventor 丁霞李园陈萌廖梦婷
Owner BEIJING UNIV OF CHINESE MEDICINE
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