Application of lycium barbarum glycopeptide in preparation of medicine for relieving neuropathic pain

A neuropathy, glycopeptide technology, applied in nervous system diseases, glycopeptide components, drug combinations, etc., can solve the problems of strong side effects, limited effect, no lycium barbarum glycopeptide to relieve pathological pain, etc., and achieve analgesic effect and obvious effect. Effect

Pending Publication Date: 2022-05-31
NINGXIA QIPEPTIDE TECH CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the current drugs for the treatment of neuropathic pain have limited effects or strong side effects.
[0003] Therefore, those skilled in the art are committed to research that can provide a mild intervention method that can play an obvious analgesic effect without obvious central side effects. At present, there is no relevant research on the relief of pathological pain by Lycium barbarum glycopeptide

Method used

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  • Application of lycium barbarum glycopeptide in preparation of medicine for relieving neuropathic pain
  • Application of lycium barbarum glycopeptide in preparation of medicine for relieving neuropathic pain
  • Application of lycium barbarum glycopeptide in preparation of medicine for relieving neuropathic pain

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Embodiment Construction

[0021] The following describes the preferred embodiments of the present invention with reference to the accompanying drawings to make the technical content clearer and easier to understand. The present invention can be embodied in many different forms of embodiments, and the protection scope of the present invention is not limited to the embodiments mentioned herein.

[0022] Nerve damage can lead to neuropathic pain, and its pathogenesis is related to central sensitization caused by glial cell activation. Studies have shown that the generation of neuropathic pain is related to neuroinflammation; and Lycium barbarum glycopeptide (LbGp), as the active ingredient extract of Lycium barbarum, has immunomodulatory effects. Therefore, the present invention studies the role of LbGp in neuropathic pain behavior by inducing neuropathic pain through chronic nerve injury.

[0023] Therefore, the present invention provides an application of Lycium barbarum glycopeptide in the preparation...

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Abstract

The invention discloses application of lycium barbarum glycopeptide in preparation of a medicine for relieving neuropathic pain, and relates to the field of lycium barbarum glycopeptide research. The invention also discloses an application of the wolfberry glycopeptide in preparation of a medicine for improving spinal microglial cell activation caused by nerve injury. The invention relates to application of wolfberry glycopeptide in preparation of a medicine for improving spinal astrocyte activation caused by nerve injury and application of wolfberry glycopeptide in preparation of a medicine for improving spinal neuron voltage-gated sodium channel Nav1.3 expression caused by nerve injury, in particular to application of wolfberry glycopeptide in preparation of a medicine for improving spinal neuron voltage-gated sodium channel Nav1.3 expression caused by nerve injury.

Description

technical field [0001] The present invention relates to the research field of efficacy of wolfberry glycopeptide, in particular to the application of wolfberry glycopeptide in medicine for relieving neuropathic pain. Background technique [0002] At present, neuropathic pain in most patients is chronic. The pain lasts beyond the healing period of the primary disease or more than 3 months. It is characterized by hyperalgesia, hyperalgesia, and spontaneous pain. Patients suffer from long-term severe physical torture and pain. The resulting psychological and emotional problems such as sleep disturbance, depression and anxiety, and mental breakdown have seriously affected the quality of life of the patients. However, most of the current therapeutic drugs for neuropathic pain have limited effects or strong side effects. [0003] Therefore, those skilled in the art are committed to research that can provide a mild intervention method, which can exert obvious analgesic effect and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/14A61P25/00A61K36/815
CPCA61K38/14A61P25/00A61K36/815
Inventor 王冬梅史永慧杨彬彬苏国辉周立兵张力任超然于哲雄李玲樊福
Owner NINGXIA QIPEPTIDE TECH CO LTD
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