Miniature biochemical analyzer using dual-spectrum detection
A biochemical analyzer, dual-spectrum technology, applied in the field of photoelectric spectrum detection and spectrum biochemical analysis, can solve the problems of lack of calibration system baseline and automatic noise elimination, unsuitable for biological sample measurement and biochemical analysis, etc. Stable and portable effect
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Embodiment 1
[0039] The structure of Example 1 is as follows figure 1 Shown. The micro biochemical analyzer of this embodiment is composed of two integrated optical micro spectrometers with the same structure and performance. One is used to measure the sample, and the other is used to measure the reference comparison sample. It is also possible to measure a sample simultaneously with two micro-spectrometers. Through reference signal processing, real-time feedback control, self-calibration, error correction, and noise reduction functions can be performed.
[0040] figure 1 The medium adaptive adjustable light source 1 emits a broad-spectrum light beam, and reaches the beam splitter 4 through the focusing collimator lens 2 and the optical attenuator 3. The transmitted light beam enters the sample chamber 5 to be tested, and is absorbed, reflected and scattered by the sample. The light beam emitted from the sample chamber enters the optical fiber 7 through the condensing lens 6. The optical fi...
Embodiment 2
[0041] An improved embodiment 2 of the present invention, such as figure 2 Shown. This embodiment includes two independent micro-spectrometers, the structure of which is mainly that a beam splitter 101 and a beam splitter 102 are added to the basic optical path of the first embodiment. The micro-spectrometers 8 and 15 can respectively compare the measured sample 5 and the reference sample 12 at the same time, and the micro-spectrometers 8 and 15 can also perform continuous spectrum scanning measurement on the same sample 5 at the same time. Due to the use of array photoelectric scanning devices, spectral scanning and photoelectric signal conversion are performed at a very high frequency. For example: above 1KHz. The influence of environment and sample instability is very small, and the noise is very low.
[0042] The micro-spectrometer in the present invention is a continuous spectrum scan. According to the measured characteristic absorption data of any component of the sample, a...
Embodiment 3
[0047] Example 3 such as Figure 4 As shown in c, the optical attenuator is composed of a polarizer 48 and an analyzer 49 placed in a coaxial position. When the polarizer 48 and the analyzer 49 are relatively rotated around the axis 50 by the driving device, the transmitted light will be change.
[0048] The position of the optical attenuator 42, the rotation angle of the disc attenuator 45, and the relative rotation angle of the polarizer 48 and the analyzer 49 of the above three embodiments all correspond to the transmittance parameters and are controlled by the adaptive system. The displacement drive and rotation drive device are connected with the computer, and the computer sends out control signals to realize feedback control.
[0049] The embodiment structure and principle of the integrated optical micro-spectrometer of the present invention are as follows Figure 5 Shown. The structure is composed of an integrated optical dispersion grating 53 and an array photodetector 54....
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Abstract
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