Quinoline coridalis B drops and preparation thereof
A technology of tetrahydropalmatine and sulfuric acid, applied in pill delivery, nervous system diseases, non-central analgesics, etc., can solve problems affecting the therapeutic effect of tetrahydropalmatine sulfate, large proportion of excipients, long disintegration time of tablets, etc. , to achieve the effect of convenient carrying and taking, reduced dosage of excipients, and small pill size
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[0020] 1. Example 1
[0021] prescription:
[0022] Tetrahydropalmatine sulfate 5g
[0023] Polyethylene glycol 6000 15g
[0024] Made into 1000 tablets
[0025] Preparation method: take the superfinely pulverized tetrahydropalmatine sulfate powder that has passed through a 200-mesh sieve, add it to the molten polyethylene glycol 6000 matrix, stir evenly, use simethicone as a coolant, make pellets by the dripping method, and dry. Got.
Example Embodiment
[0026] 2. Example 2
[0027] prescription:
[0028] Tetrahydropalmatine sulfate 5g
[0029] Polyethylene glycol 4000 15g
[0030] Made into 1000 tablets
[0031] Preparation method: Take the superfine pulverized tetrahydropalmatine sulfate powder that has passed through a 200-mesh sieve, add it to the molten polyethylene glycol 4000 matrix, stir evenly, use dimethyl silicone oil as the coolant, drip the pellets, and then dry. Got.
Example Embodiment
[0032] Three, example 3
[0033] prescription:
[0034] Tetrahydropalmatine sulfate 5g
[0035] Polyethylene glycol 6000 5g
[0036] Polyethylene glycol 4000 10g
[0037] Made into 1000 tablets
[0038] Preparation method: take the superfine pulverized tetrahydropalmatine sulfate powder that has passed through a 200-mesh sieve, add it to the molten polyethylene glycol 4000 and polyethylene glycol 6000 mixed matrix, stir evenly, use dimethyl silicone oil as a coolant, drop Preparation method: Pills are prepared, dried, and then obtained.
[0039] Four, example 4
[0040] prescription:
[0041] Tetrahydropalmatine sulfate 5g
[0042] Glyceryl monostearate 15g
[0043] Made into 1000 tablets
[0044] Preparation method: Take the superfine pulverized tetrahydropalmatine sulfate powder that has passed through a 200-mesh sieve and add it to the molten glyceryl monostearate matrix, mix it, use ice water as the coolant, drip the pellets, and dry it to obtain .
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