Bacterin of tabling gene of E type hepatitis virus

A technology of hepatitis E virus and chimeric gene, which is applied in gene therapy, antiviral agent, genetic engineering, etc., and can solve problems such as the development of HEV chimeric gene vaccine that has not yet been developed
CN1539504AInactive Publication Date: 2004-10-27ZHEJIANG ACAD OF MEDICAL SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ZHEJIANG ACAD OF MEDICAL SCI
Publication Date
2004-10-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

A chimeric gene vaccine of heaptitis E virus for preventing hepatitis E is an eukaryon expression recombinant plasmid containing the open reading frames 2(ORF2) and 3(ORF3) of hepatitis E virus.
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Description

Technical field

[0001] The invention relates to the technical field of biomedicine, and is a chimeric gene vaccine for preventing hepatitis E virus infection. Background technique

[0002] Hepatitis E is a viral hepatitis caused by hepatitis E virus (HEV). It is a relatively common infectious disease in developing countries. my country is a high-incidence area with a population infection rate of 17.2%, and it is on the rise. The disease is widespread, with severe symptoms and high mortality (average 1%-2%, up to 10%-20%). The disease is dangerous and threatens young adults. It often causes outbreaks or epidemics and brings to society Panic and economic loss. From 1986 to 1988 in the southern part of Xinjiang Uygur Autonomous Region, the largest HEV epidemic so far occurred. It lasted 20 months, with a total of 119,280 people, 72% of which were young adults aged 15-44, with a total attack rate of 2.96% and a fatality rate. 0.59%, the average fatality rate...

Claims

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