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Novel olive kernel leaf extracts and preparation process and medical use thereof

A technology for extracts and uses, which is applied in the field of Terminalia oleifera leaf extract, can solve problems such as no reports on the prevention and treatment of liver diseases and anti-tumor, and no reports on the anti-inflammatory effect of Terminalia oleifera leaf chloroform extract, and achieve anti-inflammatory effects. effect, antitumor effect

Inactive Publication Date: 2004-11-10
NANJING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are no reports on the prevention and treatment of liver diseases and anti-tumor effects of the ethanol extracts and chloroform extracts of Terminalia leaves, and there is no report on the anti-inflammatory effect of Terminalia.

Method used

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  • Novel olive kernel leaf extracts and preparation process and medical use thereof
  • Novel olive kernel leaf extracts and preparation process and medical use thereof
  • Novel olive kernel leaf extracts and preparation process and medical use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0121] Preparation of the ethanol extract of terminalia leaves:

[0122] Crumble 50g of dried terminalia leaves, add 750ml of 30% ethanol to reflux for extraction for 1 hour, filter; reflux and extract 500ml of 30% ethanol for 1 hour again; combine the two filtrates, concentrate under reduced pressure, and dry to obtain brown dry powder of ethanol extract 10.0g.

Embodiment 2

[0124] Preparation of the ethanol extract of terminalia leaves:

[0125] Crumble 50g of dried terminalia leaves, add 600ml of 50% ethanol to reflux for extraction for 1 hour, filter; reflux and extract 500ml of 50% ethanol for 1 hour again; combine the two filtrates, concentrate under reduced pressure, and dry to obtain brown dry powder of ethanol extract 11.2g.

Embodiment 3

[0127] Preparation of the ethanol extract of terminalia leaves:

[0128] Dried terminalia leaves 50g were crushed, added 750ml of 75% ethanol to soak and extract for 3 days, filtered; the dreg leaves were soaked and extracted with 600ml of 75% ethanol again for 1 day; the filtrates were combined twice, concentrated under reduced pressure, and dried to obtain brown dry powder of ethanol extract 10.5 g.

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PUM

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Abstract

The invention relates to the field of natural medicament, in particular an ethanol extract of olive kernel leaf and its medicinal usage in hepatocyte protection and anti-cancer, which has better curative effect than water extract. The invention also discloses the anti-inflammatory action of olive kernel leaf extract.

Description

[0001] Technical field The present invention relates to the field of natural medicines, and discloses a terminalia leaf extract, its preparation method and its medical application. Background technique [0002] Terminalia catappa L. is a plant of the genus Myrobalan in the Junzi family. It is native to Malaysia and is now widely distributed in tropical and subtropical regions, including India, the Philippines, Indonesia in Asia, Hainan and Taiwan in China, Africa and South Africa. , North America have introduced species. Terminalia was originally an ornamental plant, but folklore also uses its different parts to treat some diseases. Its leaves, bark and fruit are used folkly in Southeast Asia to treat dysentery, fever and to stop bleeding (T.C. Lin, Study on the tannins and related compounds in the fruit of Terminalia catappa L. J Chin Med Pharm Res, 1992, 14: 165-174 ); in Taiwan and the Philippines, it is popular to use its dry fallen leaves instead of tea to prevent and tr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P1/16A61P29/00A61P31/12A61P35/00
Inventor 高静徐力致范怡梅赵晓宁王勇汤新慧杨晓荷窦环王燕萍朱俐
Owner NANJING UNIV
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