Gatiflxacin eye gels based on HPMC medium and its preparing method

A technology of gatifloxacin and gel, which is applied in the field of medicine, can solve the problems that patients are not willing to use, low bioavailability, strong greasy feeling, etc., and achieve the goal of maintaining effective drug concentration, long residence time, and not easy to lose Effect
CN1562030AInactive Publication Date: 2005-01-12SHENYANG PHARMA UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHENYANG PHARMA UNIVERSITY
Publication Date
2005-01-12
Estimated Expiration
Not applicable · inactive patent
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Abstract

An ocular Jiatishaxing gel for treating eyelid inflammation, stye, conjunctivitis, dacryocystitis, keratitis, corneal ulcer and trachoma is prepared from Jiatishaxing, HPMC as matrix, antiseptic, isotonic regulator, osmotic promoter, pH regulator and water through dissolving Jiatishaxing in water, adding others, stirring, regulating pH=5-9, filter and adding water.
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Description

Technical field:

[0001] The invention belongs to the technical field of medicine, and relates to a gatifloxacin ophthalmic gel with HPMC as a matrix and a preparation method thereof. Background technique:

[0002] According to statistics, more than 80% of the patients who go to see a doctor in ophthalmology are ocular infection. Ophthalmic infections include conjunctivitis, keratitis, and global inflammation; divided from pathogenic bacteria, including bacterial infections and fungal infections. Anti-infective drugs can be used for bacterial infection, but due to the existence of the blood-ocular barrier, the drugs cannot fully penetrate into the eye, and the drug concentration in the intraocular tissue is low. Therefore, the anti-infective drugs used in ophthalmology are those with good permeability, such as tobramycin, cleomycin, and chloramphenicol. In recent years, the application of quinolones in ophthalmology has grown rapidly, such as ofloxacin, levofloxacin, norflo...

Claims

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